Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POLR2B
  • Mouse genes Polr2b
  • Rat genes Polr2b
  • Zfish genes polr2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Polr2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Polr2b	IDA		Mouse	PMID:22287103
Molecular Function	GO:0005515	protein binding	POLR2B	IPI	UniProtKB:Q6UXN9	Human	PMID:17998332
Molecular Function	GO:0003723	RNA binding	POLR2B	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	POLR2B	HDA		Human	PMID:22681889
Cellular Component	GO:0000781	chromosome, telomeric region	POLR2B	IDA		Human	PMID:24270157
Cellular Component	GO:0016020	membrane	POLR2B	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	POLR2B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	POLR2B	IDA		Human	PMID:9852112
Cellular Component	GO:0005665	RNA polymerase II, core complex	POLR2B	IDA		Human	PMID:9852112
Biological Process	GO:0006366	transcription by RNA polymerase II	POLR2B	IDA		Human	PMID:9852112

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern