Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POLR1E
  • Mouse genes Polr1e
  • Rat genes Polr1e
  • Zfish genes polr1e
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Polr1e

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	POLR1E	IPI	UniProtKB:Q92793	Human	PMID:24207024
Molecular Function	GO:0005515	protein binding	POLR1E	IPI	UniProtKB:Q9NRC8	Human	PMID:24207024
Molecular Function	GO:0005515	protein binding	POLR1E	IPI	UniProtKB:Q92876	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Polr1e	IPI	PR:P25976	Mouse	PMID:11592397
Molecular Function	GO:0005515	protein binding	Polr1e	IPI	PR:Q76KJ5	Mouse	PMID:15226435
Molecular Function	GO:0005515	protein binding	Polr1e	IPI	PR:P70700	Mouse	PMID:8921381
Molecular Function	GO:0005515	protein binding	Polr1e	IPI	PR:Q8QZY1	Mouse	PMID:11592397
Molecular Function	GO:0001179	RNA polymerase I general transcription initiation factor binding	Polr1e	IDA		Mouse	PMID:8641287
Cellular Component	GO:0001650	fibrillar center	POLR1E	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	Polr1e	IDA		Mouse	PMID:8641287
Cellular Component	GO:0005730	nucleolus	Polr1e	IDA		Mouse	PMID:11592397
Cellular Component	GO:0005654	nucleoplasm	POLR1E	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005736	RNA polymerase I complex	Polr1e	IDA		Mouse	PMID:8641287
Biological Process	GO:0042790	nucleolar large rRNA transcription by RNA polymerase I	POLR1E	IDA		Human	PMID:24207024
Biological Process	GO:0001188	RNA polymerase I preinitiation complex assembly	Polr1e	IDA		Mouse	PMID:8641287

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern