Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POLR1B
  • Mouse genes Polr1b
  • Rat genes Polr1b
  • Zfish genes polr1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Polr1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	Polr1b	IDA		Rat	PMID:9422795|RGD:2312782
Molecular Function	GO:0005515	protein binding	POLR1B	IPI	UniProtKB:O95602	Human	PMID:16514417
Molecular Function	GO:0005515	protein binding	POLR1B	IPI	UniProtKB:O95602	Human	PMID:19214185
Molecular Function	GO:0005515	protein binding	POLR1B	IPI	UniProtKB:Q9UPP1	Human	PMID:20208542
Molecular Function	GO:0005515	protein binding	POLR1B	IPI	UniProtKB:O95602	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	Polr1b	IPI	PR:Q8QZY1	Mouse	PMID:11592397
Molecular Function	GO:0005515	protein binding	Polr1b	IPI	PR:O35134	Mouse	PMID:9236775
Molecular Function	GO:0005515	protein binding	Polr1b	IPI	PR:Q8K202	Mouse	PMID:8921381
Molecular Function	GO:0001054	RNA polymerase I activity	polr1b	IMP	ZFIN:ZDB-MRPHLNO-200902-1	Zfish	PMID:31649276
Cellular Component	GO:0005694	chromosome	Polr1b	IDA		Mouse	MGI:MGI:6478065|PMID:30746471
Cellular Component	GO:0005694	chromosome	Polr1b	IDA		Mouse	MGI:MGI:6400008|PMID:30949703
Cellular Component	GO:0005694	chromosome	Polr1b	IDA		Mouse	MGI:MGI:6272683|PMID:30272023
Cellular Component	GO:0005829	cytosol	POLR1B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001650	fibrillar center	POLR1B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	Polr1b	IDA		Mouse	PMID:11592397
Cellular Component	GO:0005634	nucleus	Polr1b	IDA		Mouse	PMID:9236775
Cellular Component	GO:0005736	RNA polymerase I complex	Polr1b	IDA		Mouse	PMID:9236775
Cellular Component	GO:0005736	RNA polymerase I complex	Polr1b	IDA		Rat	PMID:9422795|RGD:2312782
Biological Process	GO:0009790	embryo development	Polr1b	IMP	MGI:MGI:3774130	Mouse	PMID:18023416
Biological Process	GO:0007566	embryo implantation	Polr1b	IMP	MGI:MGI:3774130	Mouse	PMID:18023416
Biological Process	GO:0001755	neural crest cell migration	polr1b	IMP	ZFIN:ZDB-MRPHLNO-200902-1	Zfish	PMID:31649276
Biological Process	GO:0014029	neural crest formation	polr1b	IMP		Zfish	PMID:31649276|ZFIN:ZDB-PUB-191029-1
Biological Process	GO:0017126	nucleologenesis	Polr1b	IMP	MGI:MGI:3774130	Mouse	PMID:18023416
Biological Process	GO:0009303	rRNA transcription	Polr1b	IMP	MGI:MGI:3774130	Mouse	PMID:18023416
Biological Process	GO:0009303	rRNA transcription	Polr1b	IDA		Rat	PMID:9422795|RGD:2312782

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern