Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POLE3
  • Mouse genes Pole3
  • Rat genes Pole3,Pole3-ps2,Pole3-ps3
  • Zfish genes pole3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pole3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	POLE3	IPI	UniProtKB:Q9NR33	Human	PMID:10801849
Molecular Function	GO:0005515	protein binding	POLE3	IPI	UniProtKB:Q01658	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	POLE3	IPI	UniProtKB:Q14919	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	POLE3	IPI	UniProtKB:Q9NRG0	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	POLE3	IPI	UniProtKB:Q9Q2G4	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	POLE3	IPI	UniProtKB:Q14919	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	POLE3	IPI	UniProtKB:Q658N3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	POLE3	IPI	UniProtKB:Q9NRG0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	POLE3	IPI	UniProtKB:Q01658	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	POLE3	IPI	UniProtKB:Q01658	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POLE3	IPI	UniProtKB:Q14919	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POLE3	IPI	UniProtKB:Q9NR33	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	POLE3	IPI	UniProtKB:Q9NRG0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pole3	IPI	PR:Q9JKP8	Mouse	PMID:11000277
Cellular Component	GO:0140672	ATAC complex	POLE3	IDA		Human	PMID:18838386
Cellular Component	GO:0008622	epsilon DNA polymerase complex	POLE3	IPI		Human	PMID:10801849
Cellular Component	GO:0008622	epsilon DNA polymerase complex	POLE3	IDA		Human	PMID:10801849
Cellular Component	GO:0005721	pericentric heterochromatin	Pole3	IDA		Mouse	MGI:MGI:6810810|PMID:12434153
Biological Process	GO:0006338	chromatin remodeling	POLE3	IDA		Human	PMID:10880450
Biological Process	GO:0006261	DNA-templated DNA replication	POLE3	IDA		Human	PMID:33051204
Biological Process	GO:0043966	histone H3 acetylation	POLE3	IDA		Human	PMID:18838386
Biological Process	GO:0006334	nucleosome assembly	POLE3	IDA		Human	PMID:14759371
Biological Process	GO:0006275	regulation of DNA replication	POLE3	IMP		Human	PMID:12434153

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern