Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PNPLA8
  • Mouse genes Pnpla8
  • Rat genes Pnpla8
  • Zfish genes pnpla8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pnpla8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	PNPLA8	IDA		Human	PMID:10744668
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	PNPLA8	IDA		Human	PMID:10833412
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	PNPLA8	IDA		Human	PMID:15695510
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	PNPLA8	IDA		Human	PMID:15908428
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	PNPLA8	IDA		Human	PMID:18171998
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	PNPLA8	IMP		Human	PMID:28442572
Molecular Function	GO:0047499	calcium-independent phospholipase A2 activity	Pnpla8	IMP		Mouse	MGI:MGI:5917216|PMID:28442572
Cellular Component	GO:0016020	membrane	PNPLA8	IDA		Human	PMID:10833412
Cellular Component	GO:0016020	membrane	PNPLA8	IDA		Human	PMID:18171998
Cellular Component	GO:0005739	mitochondrion	Pnpla8	IDA		Mouse	MGI:MGI:3708217|PMID:17213206
Cellular Component	GO:0005778	peroxisomal membrane	PNPLA8	IDA		Human	PMID:10744668
Cellular Component	GO:0005777	peroxisome	PNPLA8	IDA		Human	PMID:15695510
Cellular Component	GO:0005777	peroxisome	Pnpla8	IDA		Mouse	MGI:MGI:3708217|PMID:17213206
Biological Process	GO:0019369	arachidonic acid metabolic process	PNPLA8	IDA		Human	PMID:10833412
Biological Process	GO:0019369	arachidonic acid metabolic process	PNPLA8	IDA		Human	PMID:15695510
Biological Process	GO:0019369	arachidonic acid metabolic process	PNPLA8	IDA		Human	PMID:28442572
Biological Process	GO:0050482	arachidonic acid secretion	PNPLA8	IDA		Human	PMID:10833412
Biological Process	GO:0050482	arachidonic acid secretion	PNPLA8	IDA		Human	PMID:15695510
Biological Process	GO:0032048	cardiolipin metabolic process	PNPLA8	IDA		Human	PMID:28442572
Biological Process	GO:0032048	cardiolipin metabolic process	Pnpla8	IMP		Mouse	MGI:MGI:5917216|PMID:28442572
Biological Process	GO:0008219	cell death	PNPLA8	IDA		Human	PMID:15695510
Biological Process	GO:0006631	fatty acid metabolic process	PNPLA8	IDA		Human	PMID:10744668
Biological Process	GO:0043651	linoleic acid metabolic process	PNPLA8	IDA		Human	PMID:15695510
Biological Process	GO:0055088	lipid homeostasis	PNPLA8	IMP		Human	PMID:17213206
Biological Process	GO:0055088	lipid homeostasis	Pnpla8	IMP		Mouse	MGI:MGI:3708217|PMID:17213206
Biological Process	GO:0034638	phosphatidylcholine catabolic process	PNPLA8	IDA		Human	PMID:15695510
Biological Process	GO:0046338	phosphatidylethanolamine catabolic process	PNPLA8	IDA		Human	PMID:15695510
Biological Process	GO:0001516	prostaglandin biosynthetic process	PNPLA8	IDA		Human	PMID:15695510
Biological Process	GO:1900407	regulation of cellular response to oxidative stress	Pnpla8	IMP		Mouse	MGI:MGI:5917216|PMID:28442572
Biological Process	GO:0070328	triglyceride homeostasis	PNPLA8	IMP		Human	PMID:17213206
Biological Process	GO:0070328	triglyceride homeostasis	Pnpla8	IMP		Mouse	MGI:MGI:3708217|PMID:17213206

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern