Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PNPLA1
  • Mouse genes Pnpla1
  • Rat genes Pnpla1
  • Zfish genes pnpla1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pnpla1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	PNPLA1	IMP		Human	PMID:27751867
Molecular Function	GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	Pnpla1	IMP		Mouse	MGI:MGI:5882269|PMID:27751867
Molecular Function	GO:0106341	omega-hydroxyceramide transacylase activity	PNPLA1	IDA		Human	PMID:28248318
Molecular Function	GO:0106341	omega-hydroxyceramide transacylase activity	Pnpla1	IMP		Mouse	MGI:MGI:5888934|PMID:28248300
Molecular Function	GO:0030280	structural constituent of skin epidermis	Pnpla1	IMP		Mouse	MGI:MGI:5882269|PMID:27751867
Molecular Function	GO:0030280	structural constituent of skin epidermis	Pnpla1	IMP		Mouse	MGI:MGI:5888934|PMID:28248300
Cellular Component	GO:0005737	cytoplasm	PNPLA1	IDA		Human	PMID:22246504
Biological Process	GO:0046513	ceramide biosynthetic process	PNPLA1	IMP		Human	PMID:27751867
Biological Process	GO:0046513	ceramide biosynthetic process	Pnpla1	IMP		Mouse	MGI:MGI:5882269|PMID:27751867
Biological Process	GO:0061436	establishment of skin barrier	Pnpla1	IMP		Mouse	MGI:MGI:5882269|PMID:27751867
Biological Process	GO:0061436	establishment of skin barrier	Pnpla1	IMP		Mouse	MGI:MGI:5888934|PMID:28248300
Biological Process	GO:0030216	keratinocyte differentiation	Pnpla1	IMP		Mouse	MGI:MGI:5888934|PMID:28248300
Biological Process	GO:0030216	keratinocyte differentiation	Pnpla1	IMP		Mouse	MGI:MGI:5882269|PMID:27751867
Biological Process	GO:0106342	omega-hydroxyceramide biosynthetic process	PNPLA1	IMP		Human	PMID:28248318
Biological Process	GO:0106342	omega-hydroxyceramide biosynthetic process	Pnpla1	IMP		Mouse	MGI:MGI:5888934|PMID:28248300

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern