Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLEKHB1
  • Mouse genes Plekhb1
  • Rat genes Plekhb1
  • Zfish genes plekhb1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plekhb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PLEKHB1	IPI	UniProtKB:P52306	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Plekhb1	IPI	PR:Q9WTI7	Mouse	PMID:15976448
Molecular Function	GO:0005515	protein binding	Plekhb1	IPI	PR:P97479	Mouse	PMID:15976448
Molecular Function	GO:0042803	protein homodimerization activity	Plekhb1	IPI	UniProtKB:Q9QYE9-1	Mouse	MGI:MGI:3583854|PMID:15976448
Cellular Component	GO:0016020	membrane	PLEKHB1	IDA		Human	PMID:10585447
Biological Process	GO:0045595	regulation of cell differentiation	Plekhb1	IEP		Rat	PMID:10923244|RGD:632808

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern