Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLEKHA8,PLEKHA8P1
  • Mouse genes Plekha8
  • Rat genes Plekha8
  • Zfish genes plekha8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plekha8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097001	ceramide binding	PLEKHA8	IDA		Human	PMID:17687330
Molecular Function	GO:0051861	glycolipid binding	PLEKHA8	IDA		Human	PMID:17687330
Molecular Function	GO:0017089	glycolipid transfer activity	PLEKHA8	IDA		Human	PMID:17687330
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	PLEKHA8	IDA		Human	PMID:15107860
Cellular Component	GO:0005794	Golgi apparatus	PLEKHA8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PLEKHA8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005802	trans-Golgi network	PLEKHA8	IDA		Human	PMID:15107860
Biological Process	GO:0035621	ER to Golgi ceramide transport	PLEKHA8	IDA		Human	PMID:17687330
Biological Process	GO:0006869	lipid transport	PLEKHA8	IDA		Human	PMID:17687330

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern