Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLEKHA7
  • Mouse genes Plekha7
  • Rat genes Plekha7
  • Zfish genes plekha7a,plekha7b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plekha7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070097	delta-catenin binding	PLEKHA7	IDA		Human	PMID:19041755
Molecular Function	GO:0005515	protein binding	PLEKHA7	IPI	UniProtKB:Q14974	Human	PMID:28877994
Molecular Function	GO:0005515	protein binding	PLEKHA7	IPI	UniProtKB:Q9UKV8	Human	PMID:28877994
Molecular Function	GO:0005515	protein binding	PLEKHA7	IPI	UniProtKB:Q5EBL8|UniProtKB:Q86UF1	Human	PMID:30463011
Molecular Function	GO:0005515	protein binding	PLEKHA7	IPI	UniProtKB:Q14974	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Plekha7	IPI	UniProtKB:Q80VC9	Mouse	MGI:MGI:5532791|PMID:23990464
Molecular Function	GO:0005515	protein binding	Plekha7	IPI	UniProtKB:O60716	Mouse	MGI:MGI:5532791|PMID:23990464
Molecular Function	GO:0005515	protein binding	Plekha7	IPI	UniProtKB:O35889	Mouse	MGI:MGI:5532791|PMID:23990464
Cellular Component	GO:0030054	cell junction	PLEKHA7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005911	cell-cell junction	Plekha7	IDA		Mouse	MGI:MGI:5532791|PMID:23990464
Cellular Component	GO:0005813	centrosome	PLEKHA7	IDA		Human	PMID:19041755
Cellular Component	GO:0005829	cytosol	PLEKHA7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	PLEKHA7	HDA		Human	PMID:19056867
Cellular Component	GO:0005654	nucleoplasm	PLEKHA7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0046930	pore complex	PLEKHA7	IMP		Human	PMID:30463011
Cellular Component	GO:0046930	pore complex	Plekha7	IMP		Mouse	MGI:MGI:6316557|PMID:30463011
Cellular Component	GO:0005915	zonula adherens	PLEKHA7	IDA		Human	PMID:19041755
Biological Process	GO:0055007	cardiac muscle cell differentiation	plekha7a	IMP	ZFIN:ZDB-MRPHLNO-110824-1	Zfish	PMID:21628396
Biological Process	GO:0044331	cell-cell adhesion mediated by cadherin	Plekha7	IMP		Mouse	MGI:MGI:5532791|PMID:23990464
Biological Process	GO:0090136	epithelial cell-cell adhesion	PLEKHA7	IMP		Human	PMID:19041755
Biological Process	GO:0046931	pore complex assembly	PLEKHA7	IMP		Human	PMID:30463011
Biological Process	GO:0046931	pore complex assembly	Plekha7	IMP		Mouse	MGI:MGI:6316557|PMID:30463011
Biological Process	GO:0008016	regulation of heart contraction	plekha7a	IMP	ZFIN:ZDB-MRPHLNO-110824-1	Zfish	PMID:21628396
Biological Process	GO:0042311	vasodilation	Plekha7	IMP		Rat	PMID:25136115|RGD:11079199
Biological Process	GO:0045218	zonula adherens maintenance	PLEKHA7	IMP		Human	PMID:19041755

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern