Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLD4
  • Mouse genes Pld4
  • Rat genes Pld4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pld4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Pld4	IPI	PR:Q62277	Mouse	PMID:18706977
Molecular Function	GO:0045145	single-stranded DNA 5'-3' DNA exonuclease activity	Pld4	IMP		Mouse	MGI:MGI:5308480|PMID:22102906
Cellular Component	GO:0005769	early endosome	Pld4	IDA		Mouse	MGI:MGI:5308480|PMID:22102906
Cellular Component	GO:0005783	endoplasmic reticulum	Pld4	IDA		Mouse	PMID:21085684
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Pld4	IDA		Mouse	MGI:MGI:4849851|PMID:21085684
Cellular Component	GO:0005634	nucleus	Pld4	IDA		Mouse	PMID:22102906
Cellular Component	GO:0045335	phagocytic vesicle	Pld4	IDA		Mouse	PMID:22102906
Cellular Component	GO:0032588	trans-Golgi network membrane	Pld4	IDA		Mouse	PMID:21085684
Biological Process	GO:0051649	establishment of localization in cell	Pld4	IMP		Mouse	PMID:22102906
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Pld4	IMP		Mouse	PMID:24029230
Biological Process	GO:0006909	phagocytosis	Pld4	IMP		Mouse	PMID:22102906
Biological Process	GO:1900015	regulation of cytokine production involved in inflammatory response	Pld4	IMP		Mouse	MGI:MGI:5308480|PMID:22102906

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern