Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLA2G2D
  • Mouse genes Pla2g2d
  • Rat genes Pla2g2d
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pla2g2d

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	PLA2G2D	IDA		Human	PMID:10681567
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	Pla2g2d	IDA		Mouse	MGI:MGI:1346886|PMID:10531313
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	Pla2g2d	IDA		Mouse	MGI:MGI:5510633|PMID:23690440
Molecular Function	GO:0043395	heparan sulfate proteoglycan binding	Pla2g2d	IDA		Mouse	PMID:19564598
Molecular Function	GO:0008201	heparin binding	Pla2g2d	IDA		Mouse	PMID:19564598
Cellular Component	GO:0005576	extracellular region	Pla2g2d	IDA		Mouse	MGI:MGI:1346886|PMID:10531313
Biological Process	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Pla2g2d	IDA		Mouse	PMID:19564598
Biological Process	GO:0050868	negative regulation of T cell activation	Pla2g2d	IDA		Mouse	PMID:19564598
Biological Process	GO:0042130	negative regulation of T cell proliferation	Pla2g2d	IDA		Mouse	PMID:19564598
Biological Process	GO:0046470	phosphatidylcholine metabolic process	PLA2G2D	IDA		Human	PMID:10681567
Biological Process	GO:0046470	phosphatidylcholine metabolic process	Pla2g2d	IDA		Mouse	MGI:MGI:1346886|PMID:10531313
Biological Process	GO:0046337	phosphatidylethanolamine metabolic process	Pla2g2d	IDA		Mouse	MGI:MGI:5510633|PMID:23690440
Biological Process	GO:0046471	phosphatidylglycerol metabolic process	Pla2g2d	IDA		Mouse	MGI:MGI:1346886|PMID:10531313
Biological Process	GO:0002864	regulation of acute inflammatory response to antigenic stimulus	Pla2g2d	IMP		Mouse	MGI:MGI:5510633|PMID:23690440

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern