Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PITHD1
  • Mouse genes Pithd1
  • Rat genes Pithd1
  • Zfish genes pithd1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pithd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Pithd1	IPI	PR:Q9QUM9	Mouse	PMID:31915251
Molecular Function	GO:0005515	protein binding	Pithd1	IPI	PR:P28063	Mouse	PMID:31915251
Cellular Component	GO:0005737	cytoplasm	PITHD1	IDA		Human	PMID:25134913
Cellular Component	GO:0005737	cytoplasm	Pithd1	IDA		Mouse	PMID:31915251
Cellular Component	GO:0005634	nucleus	PITHD1	HDA		Human	PMID:21630459
Cellular Component	GO:0097598	sperm cytoplasmic droplet	Pithd1	IDA		Mouse	PMID:31915251
Biological Process	GO:0061956	penetration of cumulus oophorus	Pithd1	IMP	MGI:MGI:6416147	Mouse	PMID:31915251
Biological Process	GO:0007341	penetration of zona pellucida	Pithd1	IMP	MGI:MGI:6416147	Mouse	PMID:31915251
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	PITHD1	IDA		Human	PMID:25134913
Biological Process	GO:0045654	positive regulation of megakaryocyte differentiation	PITHD1	IMP		Human	PMID:25134913
Biological Process	GO:0045654	positive regulation of megakaryocyte differentiation	Pithd1	IMP		Mouse	MGI:MGI:6378063|PMID:25134913
Biological Process	GO:0061136	regulation of proteasomal protein catabolic process	Pithd1	IMP	MGI:MGI:6416147	Mouse	PMID:31915251
Biological Process	GO:0097722	sperm motility	Pithd1	IMP	MGI:MGI:6416147	Mouse	PMID:31915251
Biological Process	GO:0007286	spermatid development	Pithd1	IMP	MGI:MGI:6416147	Mouse	PMID:31915251

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern