Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIP4P2
  • Mouse genes Pip4p2
  • Rat genes Pip4p2
  • Zfish genes pip4p2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pip4p2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	PIP4P2	IDA		Human	PMID:16365287
Molecular Function	GO:0005515	protein binding	PIP4P2	IPI	UniProtKB:P01375	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIP4P2	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIP4P2	IPI	UniProtKB:Q5T4F4	Human	PMID:32296183
Cellular Component	GO:0031902	late endosome membrane	PIP4P2	IDA		Human	PMID:16365287
Cellular Component	GO:0031902	late endosome membrane	Pip4p2	IDA		Mouse	MGI:MGI:6144310|PMID:29378918
Cellular Component	GO:0005765	lysosomal membrane	PIP4P2	IDA		Human	PMID:16365287
Cellular Component	GO:0030670	phagocytic vesicle membrane	Pip4p2	IDA		Mouse	MGI:MGI:6144310|PMID:29378918
Cellular Component	GO:0005886	plasma membrane	Pip4p2	IDA		Mouse	MGI:MGI:6144310|PMID:29378918
Biological Process	GO:0050765	negative regulation of phagocytosis	Pip4p2	IMP		Mouse	MGI:MGI:6144310|PMID:29378918
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	PIP4P2	IDA		Human	PMID:16365287
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	Pip4p2	IMP		Mouse	MGI:MGI:6144310|PMID:29378918

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern