Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIEZO2
  • Mouse genes Piezo2
  • Rat genes Piezo2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Piezo2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008381	mechanosensitive monoatomic ion channel activity	Piezo2	IDA		Mouse	PMID:20813920
Molecular Function	GO:0005261	monoatomic cation channel activity	Piezo2	IDA		Mouse	PMID:20813920
Molecular Function	GO:0005515	protein binding	Piezo2	IPI	UniProtKB:Q6PE84	Mouse	MGI:MGI:5582997|PMID:24662763
Biological Process	GO:0050974	detection of mechanical stimulus involved in sensory perception	Piezo2	IMP		Mouse	MGI:MGI:5574426|PMID:24717433
Biological Process	GO:0006812	monoatomic cation transport	Piezo2	IMP		Mouse	MGI:MGI:4833892|PMID:20813920
Biological Process	GO:0042391	regulation of membrane potential	Piezo2	IDA		Mouse	PMID:20813920
Biological Process	GO:0009612	response to mechanical stimulus	Piezo2	IMP		Mouse	MGI:MGI:5574426|PMID:24717433

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern