Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PHACTR4
  • Mouse genes Phactr4
  • Rat genes Phactr4
  • Zfish genes phactr4a,phactr4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Phactr4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Phactr4	IDA		Mouse	MGI:MGI:3719969|PMID:17609112
Molecular Function	GO:0008157	protein phosphatase 1 binding	Phactr4	IDA		Mouse	MGI:MGI:3719969|PMID:17609112
Molecular Function	GO:0072542	protein phosphatase activator activity	Phactr4	IMP		Mouse	MGI:MGI:5302129|PMID:22215812
Molecular Function	GO:0072542	protein phosphatase activator activity	Phactr4	IDA		Mouse	MGI:MGI:3719969|PMID:17609112
Cellular Component	GO:0030027	lamellipodium	Phactr4	IDA		Mouse	MGI:MGI:5302129|PMID:22215812
Biological Process	GO:0030036	actin cytoskeleton organization	Phactr4	IMP		Mouse	MGI:MGI:5302129|PMID:22215812
Biological Process	GO:0061386	closure of optic fissure	Phactr4	IMP		Mouse	MGI:MGI:3719969|PMID:17609112
Biological Process	GO:0048484	enteric nervous system development	Phactr4	IMP		Mouse	MGI:MGI:5302129|PMID:22215812
Biological Process	GO:2001045	negative regulation of integrin-mediated signaling pathway	Phactr4	IMP		Mouse	MGI:MGI:5302129|PMID:22215812
Biological Process	GO:0001755	neural crest cell migration	Phactr4	IMP		Mouse	MGI:MGI:5302129|PMID:22215812
Biological Process	GO:0001843	neural tube closure	Phactr4	IMP		Mouse	MGI:MGI:3719969|PMID:17609112
Biological Process	GO:0043085	positive regulation of catalytic activity	Phactr4	IDA		Mouse	MGI:MGI:3719969|PMID:17609112
Biological Process	GO:0051726	regulation of cell cycle	Phactr4	IMP		Mouse	MGI:MGI:3719969|PMID:17609112
Biological Process	GO:0007266	Rho protein signal transduction	Phactr4	IMP		Mouse	MGI:MGI:5302129|PMID:22215812

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern