Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PGRMC2
  • Mouse genes Pgrmc2
  • Rat genes Pgrmc2
  • Zfish genes pgrmc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pgrmc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0020037	heme binding	PGRMC2	IDA		Human	PMID:28111073
Molecular Function	GO:0020037	heme binding	Pgrmc2	IDA		Mouse	MGI:MGI:6393146|PMID:31748741
Molecular Function	GO:0015232	heme transmembrane transporter activity	Pgrmc2	IDA		Mouse	MGI:MGI:6393146|PMID:31748741
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:P22315	Human	PMID:27599036
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9NRG9	Human	PMID:27754849
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:A0A024RCD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:I3L0A0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:O00124	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:O00264	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:O14569	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:O14681	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:O43681	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:O60636	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:O60906	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:O76064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:O95159	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:O95429	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:P01031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:P02787	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:P11215	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:P59542	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:P78329	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q01453	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q13021	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q13277	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q14656	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q5RI15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q6N075	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q6UX40	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q6ZPD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q7L5A8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q7RTY0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q86UD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q8IVQ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q8IWB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q8IWU4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q8N2M4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q8N5I4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q8N661	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q8TDV0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q96GQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q96H72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q96HH6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q96IV6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q96JF0-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q96PS8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9BTX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9BWQ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9H0Q3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9H2H9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9H2L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9H3K2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9H9B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9NZ01	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9P0L0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9P0S3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9UBY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9Y342	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PGRMC2	IPI	UniProtKB:Q9Y5Y5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pgrmc2	IPI	UniProtKB:O55022	Mouse	MGI:MGI:6393146|PMID:31748741
Molecular Function	GO:0005515	protein binding	Pgrmc2	IPI	PR:Q8K3I9	Mouse	PMID:11591653
Cellular Component	GO:0005783	endoplasmic reticulum	PGRMC2	IDA		Human	PMID:27754849
Cellular Component	GO:0016020	membrane	PGRMC2	HDA		Human	PMID:19946888
Cellular Component	GO:0005635	nuclear envelope	PGRMC2	IDA		Human	PMID:25468996
Cellular Component	GO:0005635	nuclear envelope	PGRMC2	IDA		Human	PMID:27754849
Cellular Component	GO:0005635	nuclear envelope	PGRMC2	IDA		Human	PMID:28111073
Biological Process	GO:0060612	adipose tissue development	PGRMC2	IMP		Human	PMID:28111073
Biological Process	GO:0015886	heme transport	Pgrmc2	IDA		Mouse	MGI:MGI:6393146|PMID:31748741
Biological Process	GO:0001556	oocyte maturation	pgrmc2	IMP	ZFIN:ZDB-GENO-201001-4	Zfish	PMID:31536721
Biological Process	GO:0030728	ovulation	pgrmc2	IMP	ZFIN:ZDB-GENO-201001-4	Zfish	PMID:31536721

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern