Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PFDN2
  • Mouse genes Pfdn2
  • Rat genes Pfdn2
  • Zfish genes pfdn2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pfdn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001540	amyloid-beta binding	PFDN2	IDA		Human	PMID:23614719
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:O94763	Human	PMID:15923622
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:O60925	Human	PMID:16876117
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:P0C045	Human	PMID:16876117
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:O94763	Human	PMID:17936702
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:O94763	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:Q99471	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:Q9H6T3	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:Q9NUG6	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:Q9UBK9	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:O60925	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:P61758	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:Q99471	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:Q9NUG6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:Q9UBK9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:A6NNF4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:P07108-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:P61758	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:Q99471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:P31930	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:P61758	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PFDN2	IPI	UniProtKB:P63000	Human	PMID:32814053
Molecular Function	GO:0044183	protein folding chaperone	PFDN2	IPI	UniProtKB:O60925	Human	PMID:16876117
Molecular Function	GO:0051082	unfolded protein binding	PFDN2	IDA		Human	PMID:30955883
Cellular Component	GO:0005737	cytoplasm	PFDN2	IDA		Human	PMID:16876117
Cellular Component	GO:0005737	cytoplasm	PFDN2	IDA		Human	PMID:17936702
Cellular Component	GO:0005829	cytosol	PFDN2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	PFDN2	IDA		Human	PMID:17936702
Cellular Component	GO:0005634	nucleus	PFDN2	IDA		Human	PMID:16876117
Cellular Component	GO:0005634	nucleus	PFDN2	IDA		Human	PMID:17936702
Cellular Component	GO:0016272	prefoldin complex	PFDN2	IDA		Human	PMID:23614719
Cellular Component	GO:0016272	prefoldin complex	PFDN2	IDA		Human	PMID:30955883
Cellular Component	GO:1990062	RPAP3/R2TP/prefoldin-like complex	PFDN2	IPI		Human	PMID:31738558
Biological Process	GO:1905907	negative regulation of amyloid fibril formation	PFDN2	IDA		Human	PMID:23614719
Biological Process	GO:0051495	positive regulation of cytoskeleton organization	PFDN2	IDA		Human	PMID:16876117
Biological Process	GO:0006457	protein folding	PFDN2	IDA		Human	PMID:30955883
Biological Process	GO:0006457	protein folding	Pfdn2	IDA		Mouse	PMID:9630229

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern