Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PFDN1
  • Mouse genes Pfdn1
  • Rat genes Pfdn1
  • Zfish genes pfdn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pfdn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001540	amyloid-beta binding	PFDN1	IDA		Human	PMID:23614719
Molecular Function	GO:0005515	protein binding	PFDN1	IPI	UniProtKB:Q9UHV9	Human	PMID:16876117
Molecular Function	GO:0005515	protein binding	PFDN1	IPI	UniProtKB:Q9UHV9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PFDN1	IPI	UniProtKB:Q9NPF5	Human	PMID:32296183
Molecular Function	GO:0044183	protein folding chaperone	PFDN1	IPI	UniProtKB:Q9UHV9	Human	PMID:16876117
Molecular Function	GO:0051082	unfolded protein binding	PFDN1	IDA		Human	PMID:30955883
Cellular Component	GO:0016272	prefoldin complex	PFDN1	IDA		Human	PMID:23614719
Cellular Component	GO:0016272	prefoldin complex	PFDN1	IDA		Human	PMID:30955883
Biological Process	GO:0030036	actin cytoskeleton organization	Pfdn1	IMP	MGI:MGI:3800373	Mouse	PMID:18566413
Biological Process	GO:0042113	B cell activation	Pfdn1	IMP	MGI:MGI:3800373	Mouse	PMID:18566413
Biological Process	GO:0021549	cerebellum development	Pfdn1	IMP	MGI:MGI:3800373	Mouse	PMID:18566413
Biological Process	GO:1905907	negative regulation of amyloid fibril formation	PFDN1	IDA		Human	PMID:23614719
Biological Process	GO:0006457	protein folding	PFDN1	IDA		Human	PMID:30955883
Biological Process	GO:0021537	telencephalon development	Pfdn1	IMP	MGI:MGI:3800373	Mouse	PMID:18566413

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern