Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PDHX
  • Mouse genes Pdhx
  • Rat genes Pdhx
  • Zfish genes pdhx
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pdhx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PDHX	IPI	UniProtKB:P09622	Human	PMID:16263718
Molecular Function	GO:0005515	protein binding	PDHX	IPI	UniProtKB:P09622	Human	PMID:16442803
Molecular Function	GO:0005515	protein binding	PDHX	IPI	UniProtKB:Q6RW13	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	PDHX	IPI	UniProtKB:Q6RW13	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PDHX	IPI	UniProtKB:Q9Y6E7	Human	PMID:25525879
Molecular Function	GO:0005515	protein binding	PDHX	IPI	UniProtKB:P09622	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PDHX	IPI	UniProtKB:Q6RW13	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PDHX	IPI	UniProtKB:P09622	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PDHX	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Molecular Function	GO:0034604	pyruvate dehydrogenase (NAD+) activity	PDHX	IDA		Human	PMID:9242632
Cellular Component	GO:0005967	mitochondrial pyruvate dehydrogenase complex	PDHX	IPI		Human	PMID:19240034
Cellular Component	GO:0005739	mitochondrion	Pdhx	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Pdhx	HDA		Mouse	PMID:14651853
Cellular Component	GO:0045254	pyruvate dehydrogenase complex	PDHX	IDA		Human	PMID:25525879
Cellular Component	GO:0045254	pyruvate dehydrogenase complex	PDHX	IDA		Human	PMID:9242632
Biological Process	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	PDHX	IDA		Human	PMID:24534072

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern