Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PDE1A
  • Mouse genes Pde1a
  • Rat genes Pde1a
  • Zfish genes pde1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pde1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	Pde1a	IDA		Mouse	MGI:MGI:6355909|PMID:15901640
Molecular Function	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	Pde1a	IDA		Mouse	MGI:MGI:6355909|PMID:15901640
Molecular Function	GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	Pde1a	IDA		Mouse	MGI:MGI:6355909|PMID:15901640
Molecular Function	GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	Pde1a	IMP		Rat	PMID:16514069|RGD:2312521
Molecular Function	GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	PDE1A	IDA		Human	PMID:8557689
Molecular Function	GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	Pde1a	IDA		Mouse	MGI:MGI:6355909|PMID:15901640
Cellular Component	GO:0005737	cytoplasm	Pde1a	IDA		Rat	PMID:16514069|RGD:2312521
Cellular Component	GO:0043025	neuronal cell body	Pde1a	IDA		Rat	PMID:16881052|RGD:2312522
Cellular Component	GO:0005634	nucleus	Pde1a	IDA		Rat	PMID:16514069|RGD:2312521
Cellular Component	GO:0036126	sperm flagellum	Pde1a	IDA		Mouse	MGI:MGI:6355909|PMID:15901640
Biological Process	GO:0046069	cGMP catabolic process	Pde1a	IMP		Rat	PMID:16514069|RGD:2312521
Biological Process	GO:0048793	pronephros development	pde1a	IGI	ZFIN:ZDB-MRPHLNO-060630-4,ZFIN:ZDB-MRPHLNO-150814-3	Zfish	PMID:24700876
Biological Process	GO:0048793	pronephros development	pde1a	IMP	ZFIN:ZDB-MRPHLNO-150814-4	Zfish	PMID:24700876
Biological Process	GO:0048793	pronephros development	pde1a	IMP	ZFIN:ZDB-MRPHLNO-150814-3	Zfish	PMID:24700876
Biological Process	GO:0048793	pronephros development	pde1a	IMP	ZFIN:ZDB-MRPHLNO-150814-2	Zfish	PMID:24700876
Biological Process	GO:0048793	pronephros development	pde1a	IMP	ZFIN:ZDB-MRPHLNO-150814-1	Zfish	PMID:24700876
Biological Process	GO:0034391	regulation of smooth muscle cell apoptotic process	Pde1a	IMP		Rat	PMID:16514069|RGD:2312521
Biological Process	GO:0048660	regulation of smooth muscle cell proliferation	Pde1a	IMP		Rat	PMID:16514069|RGD:2312521

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern