Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PDCD1
  • Mouse genes Pdcd1
  • Rat genes Pdcd1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pdcd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PDCD1	IPI	UniProtKB:Q06124	Human	PMID:15240681
Molecular Function	GO:0005515	protein binding	PDCD1	IPI	UniProtKB:Q4QTK1	Human	PMID:17489864
Molecular Function	GO:0005515	protein binding	PDCD1	IPI	UniProtKB:Q9BQ51	Human	PMID:20587542
Molecular Function	GO:0005515	protein binding	PDCD1	IPI	UniProtKB:Q9NZQ7	Human	PMID:20587542
Molecular Function	GO:0005515	protein binding	PDCD1	IPI	UniProtKB:Q9NZQ7	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	PDCD1	IPI	UniProtKB:Q9BQ51	Human	PMID:23417675
Molecular Function	GO:0005515	protein binding	PDCD1	IPI	UniProtKB:Q9NZQ7	Human	PMID:23417675
Molecular Function	GO:0005515	protein binding	PDCD1	IPI	UniProtKB:Q9NZQ7-1	Human	PMID:26602187
Molecular Function	GO:0005515	protein binding	PDCD1	IPI	UniProtKB:Q06124	Human	PMID:28046066
Molecular Function	GO:0005515	protein binding	PDCD1	IPI	UniProtKB:Q6PIJ6	Human	PMID:30487606
Molecular Function	GO:0005515	protein binding	Pdcd1	IPI	UniProtKB:Q9EP73	Mouse	MGI:MGI:6189321|PMID:23417675
Molecular Function	GO:0005515	protein binding	Pdcd1	IPI	UniProtKB:Q9EP73|UniProtKB:Q9WUL5	Mouse	MGI:MGI:3807128|PMID:18641123
Molecular Function	GO:0005515	protein binding	Pdcd1	IPI	UniProtKB:Q9EP73	Mouse	MGI:MGI:5315328|PMID:21884581
Molecular Function	GO:0005515	protein binding	Pdcd1	IPI	PR:Q9EP73	Mouse	PMID:15568026
Cellular Component	GO:0009897	external side of plasma membrane	Pdcd1	IDA		Mouse	PMID:23583643
Cellular Component	GO:0009897	external side of plasma membrane	Pdcd1	IDA		Mouse	PMID:15568026
Cellular Component	GO:0005886	plasma membrane	Pdcd1	IDA		Rat	PMID:24165459|RGD:9589083
Biological Process	GO:0001783	B cell apoptotic process	Pdcd1	IMP		Mouse	PMID:23636058
Biological Process	GO:0002903	negative regulation of B cell apoptotic process	Pdcd1	IMP		Mouse	PMID:23636058
Biological Process	GO:0050777	negative regulation of immune response	Pdcd1	IMP		Mouse	MGI:MGI:1929567|PMID:11209085
Biological Process	GO:0050777	negative regulation of immune response	Pdcd1	IMP		Mouse	MGI:MGI:2386198|PMID:10485649
Biological Process	GO:0002644	negative regulation of tolerance induction	Pdcd1	IMP		Mouse	PMID:23636058
Biological Process	GO:0070234	positive regulation of T cell apoptotic process	PDCD1	IDA		Human	PMID:25281059
Biological Process	GO:0070234	positive regulation of T cell apoptotic process	Pdcd1	IMP		Mouse	PMID:23636058
Biological Process	GO:1902482	regulatory T cell apoptotic process	Pdcd1	IMP		Mouse	PMID:23636058

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern