Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PBK
  • Mouse genes Pbk
  • Rat genes Pbk
  • Zfish genes pbk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pbk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PBK	IPI	UniProtKB:Q12959	Human	PMID:10779557
Molecular Function	GO:0005515	protein binding	PBK	IPI	UniProtKB:P10398	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	PBK	IPI	UniProtKB:P04637	Human	PMID:17482142
Molecular Function	GO:0005515	protein binding	PBK	IPI	UniProtKB:P04637	Human	PMID:20622899
Molecular Function	GO:0005515	protein binding	PBK	IPI	UniProtKB:Q8TF50	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBK	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PBK	IPI	UniProtKB:Q96EZ8	Human	PMID:32296183
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Pbk	IDA		Mouse	PMID:21715333
Cellular Component	GO:0005634	nucleus	PBK	IDA		Human	PMID:25575812
Biological Process	GO:0034644	cellular response to UV	Pbk	IMP	MGI:MGI:5293435	Mouse	PMID:21715333
Biological Process	GO:0050728	negative regulation of inflammatory response	Pbk	IMP	MGI:MGI:5293435	Mouse	PMID:21715333
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Pbk	IMP	MGI:MGI:5293435	Mouse	PMID:21715333
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Pbk	IMP	MGI:MGI:5293435	Mouse	PMID:21715333
Biological Process	GO:0032873	negative regulation of stress-activated MAPK cascade	Pbk	IMP	MGI:MGI:5293435	Mouse	PMID:21715333
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Pbk	IMP	MGI:MGI:5293435	Mouse	PMID:21715333
Biological Process	GO:0006468	protein phosphorylation	Pbk	IMP	MGI:MGI:5293435	Mouse	PMID:21715333
Biological Process	GO:0051403	stress-activated MAPK cascade	Pbk	IMP	MGI:MGI:5293435	Mouse	PMID:21715333

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern