Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PARP14
  • Mouse genes Parp14
  • Rat genes Parp14
  • Zfish genes parp14rs1,parp14rs4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Parp14

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	PARP14	IPI	UniProtKB:Q8IXQ6	Human	PMID:27796300
Molecular Function	GO:0003950	NAD+ ADP-ribosyltransferase activity	PARP14	IDA		Human	PMID:27796300
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP14	IDA		Human	PMID:18851833
Molecular Function	GO:1990404	NAD+-protein ADP-ribosyltransferase activity	PARP14	IDA		Human	PMID:25043379
Molecular Function	GO:0005515	protein binding	PARP14	IPI	UniProtKB:Q460N3	Human	PMID:23473667
Molecular Function	GO:0005515	protein binding	PARP14	IPI	UniProtKB:Q53GL7	Human	PMID:23473667
Molecular Function	GO:0005515	protein binding	Parp14	IPI	UniProtKB:P52633	Mouse	MGI:MGI:3621509|PMID:16537510
Molecular Function	GO:0005515	protein binding	Parp14	IPI	UniProtKB:Q53GL7	Mouse	MGI:MGI:5897545|PMID:23473667
Molecular Function	GO:0005515	protein binding	Parp14	IPI	UniProtKB:P06745	Mouse	MGI:MGI:3722693|PMID:17875708
Cellular Component	GO:0005737	cytoplasm	PARP14	IDA		Human	PMID:27796300
Cellular Component	GO:0005737	cytoplasm	Parp14	IDA		Mouse	MGI:MGI:5897545|PMID:23473667
Cellular Component	GO:0005829	cytosol	PARP14	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	PARP14	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	PARP14	IDA		Human	GO_REF:0000052
Biological Process	GO:0010629	negative regulation of gene expression	PARP14	IMP		Human	PMID:27796300
Biological Process	GO:0060336	negative regulation of type II interferon-mediated signaling pathway	PARP14	IMP		Human	PMID:27796300
Biological Process	GO:0060336	negative regulation of type II interferon-mediated signaling pathway	Parp14	IMP		Mouse	MGI:MGI:5905929|PMID:27796300
Biological Process	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	PARP14	IMP		Human	PMID:27796300
Biological Process	GO:1902216	positive regulation of interleukin-4-mediated signaling pathway	PARP14	IMP		Human	PMID:27796300
Biological Process	GO:1902216	positive regulation of interleukin-4-mediated signaling pathway	Parp14	IMP		Mouse	MGI:MGI:5905929|PMID:27796300
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	PARP14	IMP		Human	PMID:27796300

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern