Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PALS2
  • Mouse genes Pals2
  • Rat genes Pals2
  • Zfish genes pals2a,pals2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pals2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PALS2	IPI	UniProtKB:O14910	Human	PMID:11311936
Molecular Function	GO:0005515	protein binding	PALS2	IPI	UniProtKB:O14910	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	PALS2	IPI	UniProtKB:Q9NUP9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PALS2	IPI	UniProtKB:O14910	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PALS2	IPI	UniProtKB:Q9HAP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PALS2	IPI	UniProtKB:Q9NUP9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pals2	IPI	UniProtKB:Q8R5M8	Mouse	MGI:MGI:2675176|PMID:12826663
Molecular Function	GO:0005515	protein binding	Pals2	IPI	UniProtKB:O70318	Mouse	MGI:MGI:5318920|PMID:22025680
Molecular Function	GO:0005515	protein binding	Pals2	IPI	PR:Q8VHG2	Mouse	PMID:18824598
Cellular Component	GO:0070062	extracellular exosome	PALS2	HDA		Human	PMID:20458337
Cellular Component	GO:0005886	plasma membrane	Pals2	IDA		Mouse	PMID:10753959
Biological Process	GO:0021782	glial cell development	pals2b	IMP	ZFIN:ZDB-CRISPR-191009-39,ZFIN:ZDB-CRISPR-191009-40	Zfish	PMID:30924555
Biological Process	GO:0060041	retina development in camera-type eye	pals2b	IMP	ZFIN:ZDB-CRISPR-191009-39,ZFIN:ZDB-CRISPR-191009-40	Zfish	PMID:30924555

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern