Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PAH
  • Mouse genes Pah
  • Rat genes Pah
  • Zfish genes pah
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pah

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016597	amino acid binding	Pah	IDA		Rat	PMID:16953590|RGD:1601531
Molecular Function	GO:0042802	identical protein binding	Pah	IPI	RGD:3248	Rat	PMID:10331871|RGD:1601548
Molecular Function	GO:0005506	iron ion binding	Pah	IDA		Rat	PMID:10331871|RGD:1601548
Molecular Function	GO:0004505	phenylalanine 4-monooxygenase activity	PAH	IDA		Human	PMID:20667834
Molecular Function	GO:0004505	phenylalanine 4-monooxygenase activity	Pah	IMP	MGI:MGI:1857271	Mouse	PMID:2308957
Molecular Function	GO:0004505	phenylalanine 4-monooxygenase activity	Pah	IDA		Rat	PMID:10839989|RGD:1601535
Molecular Function	GO:0004505	phenylalanine 4-monooxygenase activity	Pah	IDA		Rat	PMID:16953590|RGD:1601531
Biological Process	GO:0071391	cellular response to estrogen stimulus	pah	IDA		Zfish	PMID:18618001
Biological Process	GO:0006558	L-phenylalanine metabolic process	Pah	IDA		Rat	PMID:16953590|RGD:1601531
Biological Process	GO:0018126	protein hydroxylation	Pah	IDA		Rat	PMID:16953590|RGD:1601531
Biological Process	GO:0006571	tyrosine biosynthetic process	Pah	IDA		Rat	PMID:16953590|RGD:1601531
Biological Process	GO:0019293	tyrosine biosynthetic process, by oxidation of phenylalanine	Pah	IMP	MGI:MGI:1857271	Mouse	MGI:MGI:58807|PMID:2308957
Biological Process	GO:0019293	tyrosine biosynthetic process, by oxidation of phenylalanine	Pah	IDA		Rat	PMID:10839989|RGD:1601535

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern