Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PADI6
  • Mouse genes Padi6
  • Rat genes Padi6
  • Zfish genes padi2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Padi6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140794	histone arginine deiminase activity	padi2	IMP	ZFIN:ZDB-GENO-210506-12	Zfish	PMID:32328635
Molecular Function	GO:0005515	protein binding	PADI6	IPI	UniProtKB:O43463	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PADI6	IPI	UniProtKB:O95198	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PADI6	IPI	UniProtKB:Q8TF50	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PADI6	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Padi6	IPI	PR:P68254	Mouse	PMID:18463355
Molecular Function	GO:0004668	protein-arginine deiminase activity	Padi6	IMP	MGI:MGI:3806009	Mouse	PMID:17587491
Cellular Component	GO:0060473	cortical granule	Padi6	IDA		Mouse	MGI:MGI:6508663|PMID:16137333
Cellular Component	GO:0005737	cytoplasm	PADI6	IDA		Human	PMID:27545678
Cellular Component	GO:0005737	cytoplasm	Padi6	IDA		Mouse	PMID:12654293
Cellular Component	GO:0005737	cytoplasm	Padi6	IDA		Mouse	PMID:20830304
Cellular Component	GO:0045111	intermediate filament cytoskeleton	Padi6	IDA		Mouse	PMID:12654293
Biological Process	GO:0007028	cytoplasm organization	Padi6	IMP	MGI:MGI:3806009	Mouse	PMID:18599511
Biological Process	GO:0007010	cytoskeleton organization	Padi6	IMP	MGI:MGI:3806009	Mouse	PMID:17587491
Biological Process	GO:0040016	embryonic cleavage	Padi6	IDA		Mouse	MGI:MGI:6508663|PMID:16137333
Biological Process	GO:0008104	protein localization	Padi6	IMP	MGI:MGI:3806009	Mouse	PMID:18599511
Biological Process	GO:0043143	regulation of translation by machinery localization	Padi6	IMP	MGI:MGI:3806009	Mouse	PMID:18599511
Biological Process	GO:0001944	vasculature development	padi2	IMP	ZFIN:ZDB-MRPHLNO-170818-2	Zfish	PMID:28617813
Biological Process	GO:0001944	vasculature development	padi2	IMP	ZFIN:ZDB-MRPHLNO-170818-1	Zfish	PMID:28617813

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern