Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PADI2
  • Mouse genes Padi2
  • Rat genes Padi2
  • Zfish genes padi2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Padi2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140794	histone arginine deiminase activity	padi2	IMP	ZFIN:ZDB-GENO-210506-12	Zfish	PMID:32328635
Molecular Function	GO:0140798	histone H3R26 arginine deiminase activity	PADI2	IDA		Human	PMID:22853951
Molecular Function	GO:0030331	nuclear estrogen receptor binding	PADI2	IPI	UniProtKB:P03372	Human	PMID:22853951
Molecular Function	GO:0042803	protein homodimerization activity	PADI2	IDA		Human	PMID:25621824
Molecular Function	GO:0004668	protein-arginine deiminase activity	PADI2	IDA		Human	PMID:12392711
Molecular Function	GO:0004668	protein-arginine deiminase activity	PADI2	IDA		Human	PMID:15629448
Molecular Function	GO:0004668	protein-arginine deiminase activity	PADI2	IDA		Human	PMID:18645041
Molecular Function	GO:0004668	protein-arginine deiminase activity	PADI2	IDA		Human	PMID:25621824
Molecular Function	GO:0004668	protein-arginine deiminase activity	Padi2	IDA		Rat	PMID:12392711|RGD:8554540
Cellular Component	GO:0005737	cytoplasm	PADI2	IDA		Human	PMID:12392711
Cellular Component	GO:0000791	euchromatin	PADI2	IDA		Human	PMID:22853951
Cellular Component	GO:0070062	extracellular exosome	PADI2	HDA		Human	PMID:19056867
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Padi2	IEP		Mouse	PMID:20439489
Biological Process	GO:0030520	intracellular estrogen receptor signaling pathway	PADI2	IMP		Human	PMID:22853951
Biological Process	GO:0070100	negative regulation of chemokine-mediated signaling pathway	PADI2	IDA		Human	PMID:18645041
Biological Process	GO:1901624	negative regulation of lymphocyte chemotaxis	PADI2	IDA		Human	PMID:18645041
Biological Process	GO:0021762	substantia nigra development	PADI2	HEP		Human	PMID:22926577
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	PADI2	IMP		Human	PMID:22853951
Biological Process	GO:0001944	vasculature development	padi2	IMP	ZFIN:ZDB-MRPHLNO-170818-2	Zfish	PMID:28617813
Biological Process	GO:0001944	vasculature development	padi2	IMP	ZFIN:ZDB-MRPHLNO-170818-1	Zfish	PMID:28617813

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern