Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes P2RY4
  • Mouse genes P2ry4
  • Rat genes P2ry4
  • Zfish genes p2ry2.1,p2ry2.2,p2ry2.3,p2ry4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set P2ry4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	P2ry4	IDA		Rat	PMID:11557527|RGD:628452
Molecular Function	GO:0045030	G protein-coupled UTP receptor activity	P2ry4	IDA		Mouse	PMID:11259526
Molecular Function	GO:0005515	protein binding	P2RY4	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Cellular Component	GO:0016324	apical plasma membrane	P2ry4	IDA		Rat	PMID:11557527|RGD:628452
Cellular Component	GO:0016323	basolateral plasma membrane	P2ry4	IDA		Rat	PMID:11557527|RGD:628452
Cellular Component	GO:0098978	glutamatergic synapse	P2ry4	EXP		Rat	PMID:16000618|RGD:1581702
Cellular Component	GO:0098978	glutamatergic synapse	P2ry4	IDA		Rat	PMID:16000618|RGD:1581702
Cellular Component	GO:0048787	presynaptic active zone membrane	P2ry4	IDA		Rat	PMID:16000618|RGD:1581702
Biological Process	GO:0071380	cellular response to prostaglandin E stimulus	P2ry4	IDA		Mouse	PMID:23479225
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	P2ry4	EXP		Rat	PMID:16000618|RGD:1581702
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	P2ry4	IDA		Rat	PMID:16000618|RGD:1581702
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	P2ry4	IEP		Rat	PMID:16000618|RGD:1581702
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	P2ry4	EXP		Rat	PMID:16000618|RGD:1581702
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	P2ry4	IDA		Rat	PMID:16000618|RGD:1581702
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	P2ry4	IEP		Rat	PMID:16000618|RGD:1581702
Biological Process	GO:0030321	transepithelial chloride transport	P2ry4	IDA		Mouse	PMID:11259526

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern