Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OSMR
  • Mouse genes Osmr
  • Rat genes Osmr
  • Zfish genes lifra,lifrb,osmr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Osmr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019955	cytokine binding	Osmr	IPI	PR:Q6EAL8	Mouse	PMID:21182835
Molecular Function	GO:0019838	growth factor binding	OSMR	IPI	UniProtKB:P13725	Human	PMID:8999038
Molecular Function	GO:0004924	oncostatin-M receptor activity	OSMR	IDA		Human	PMID:8999038
Molecular Function	GO:0004924	oncostatin-M receptor activity	Osmr	IDA		Mouse	PMID:9920829
Molecular Function	GO:0005515	protein binding	OSMR	IPI	UniProtKB:P40189	Human	PMID:24501689
Molecular Function	GO:0005515	protein binding	OSMR	IPI	UniProtKB:P50458	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OSMR	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OSMR	IPI	UniProtKB:Q96EQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OSMR	IPI	UniProtKB:Q9NZD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OSMR	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	OSMR	IPI	UniProtKB:O75306	Human	PMID:32807793
Molecular Function	GO:0005515	protein binding	OSMR	IPI	UniProtKB:P28331	Human	PMID:32807793
Molecular Function	GO:0005515	protein binding	OSMR	IPI	UniProtKB:P38646	Human	PMID:32807793
Molecular Function	GO:0005515	protein binding	OSMR	IPI	UniProtKB:Q9UII2	Human	PMID:32807793
Cellular Component	GO:0016324	apical plasma membrane	OSMR	IDA		Human	PMID:21912637
Cellular Component	GO:0009897	external side of plasma membrane	Osmr	IDA		Mouse	PMID:21182835
Cellular Component	GO:0005900	oncostatin-M receptor complex	OSMR	IDA		Human	PMID:8999038
Biological Process	GO:0038165	oncostatin-M-mediated signaling pathway	OSMR	IMP		Human	PMID:8999038
Biological Process	GO:0008284	positive regulation of cell population proliferation	OSMR	IGI		Human	PMID:8999038
Biological Process	GO:0034097	response to cytokine	OSMR	IDA		Human	PMID:8999038

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern