Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OSM
  • Mouse genes Osm
  • Rat genes Osm
  • Zfish genes osm
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Osm

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005125	cytokine activity	OSM	IDA		Human	PMID:8999038
Molecular Function	GO:0005125	cytokine activity	Osm	IDA		Mouse	PMID:15012602
Molecular Function	GO:0008083	growth factor activity	OSM	IDA		Human	PMID:8999038
Molecular Function	GO:0005147	oncostatin-M receptor binding	OSM	IPI	UniProtKB:P40189	Human	PMID:8999038
Molecular Function	GO:0005147	oncostatin-M receptor binding	OSM	IPI	UniProtKB:Q99650	Human	PMID:8999038
Molecular Function	GO:0005515	protein binding	OSM	IPI	UniProtKB:P40189	Human	PMID:16051226
Molecular Function	GO:0005515	protein binding	OSM	IPI	UniProtKB:P40189	Human	PMID:28514442
Biological Process	GO:0048266	behavioral response to pain	Osm	IMP	MGI:MGI:3574987	Mouse	PMID:14985435
Biological Process	GO:0140013	meiotic nuclear division	Osm	IDA		Mouse	PMID:11203703
Biological Process	GO:0046888	negative regulation of hormone secretion	OSM	IDA		Human	PMID:7867561
Biological Process	GO:0045835	negative regulation of meiotic nuclear division	Osm	IDA		Mouse	PMID:11203703
Biological Process	GO:0038165	oncostatin-M-mediated signaling pathway	OSM	IDA		Human	PMID:8999038
Biological Process	GO:0007422	peripheral nervous system development	Osm	IMP	MGI:MGI:3574987	Mouse	PMID:14985435
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	Osm	IDA		Mouse	PMID:15012602
Biological Process	GO:0008284	positive regulation of cell population proliferation	OSM	IDA		Human	PMID:8999038
Biological Process	GO:0050729	positive regulation of inflammatory response	OSM	IDA		Human	PMID:28972028
Biological Process	GO:0032740	positive regulation of interleukin-17 production	OSM	IDA		Human	PMID:28972028
Biological Process	GO:0043410	positive regulation of MAPK cascade	OSM	IDA		Human	PMID:7508917
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	OSM	IDA		Human	PMID:7508917
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	OSM	IDA		Human	PMID:7508917
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	OSM	IDA		Human	PMID:8999038
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Osm	IDA		Mouse	PMID:24129709
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	OSM	IGI	RNAcentral:URS0000574A2C_9606	Human	PMID:28972028
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	OSM	IGI	RNAcentral:URS0000574A2C_9606	Human	PMID:28972028
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	OSM	IDA		Human	PMID:7508917
Biological Process	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	OSM	IDA		Human	PMID:21912637
Biological Process	GO:0009408	response to heat	Osm	IMP	MGI:MGI:3574987	Mouse	PMID:14985435
Biological Process	GO:0007260	tyrosine phosphorylation of STAT protein	Osm	IDA		Mouse	PMID:15012602

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern