Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OSBPL8
  • Mouse genes Osbpl8
  • Rat genes Osbpl8
  • Zfish genes osbpl8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Osbpl8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015485	cholesterol binding	OSBPL8	IDA		Human	PMID:17428193
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	OSBPL8	IDA		Human	PMID:26206935
Molecular Function	GO:0001786	phosphatidylserine binding	OSBPL8	IDA		Human	PMID:26206935
Molecular Function	GO:0140343	phosphatidylserine transfer activity	OSBPL8	IDA		Human	PMID:26206935
Molecular Function	GO:0005515	protein binding	OSBPL8	IPI	UniProtKB:Q96R06	Human	PMID:24424245
Molecular Function	GO:0005515	protein binding	Osbpl8	IPI	PR:O35250	Mouse	PMID:21441927
Cellular Component	GO:0016020	membrane	OSBPL8	HDA		Human	PMID:19946888
Cellular Component	GO:0031965	nuclear membrane	Osbpl8	IMP		Mouse	PMID:22683860
Biological Process	GO:0032148	activation of protein kinase B activity	Osbpl8	IMP		Mouse	MGI:MGI:5644010|PMID:23812417
Biological Process	GO:0045444	fat cell differentiation	OSBPL8	IDA		Human	PMID:23028956
Biological Process	GO:0030336	negative regulation of cell migration	Osbpl8	IMP		Mouse	PMID:21441927
Biological Process	GO:0010891	negative regulation of sequestering of triglyceride	OSBPL8	IDA		Human	PMID:23028956
Biological Process	GO:0015914	phospholipid transport	OSBPL8	IDA		Human	PMID:26206935
Biological Process	GO:0046326	positive regulation of glucose import	Osbpl8	IMP		Mouse	MGI:MGI:5644010|PMID:23812417
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	Osbpl8	IDA		Mouse	MGI:MGI:5644010|PMID:23812417
Biological Process	GO:0046628	positive regulation of insulin receptor signaling pathway	Osbpl8	IMP		Mouse	PMID:21441927
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Osbpl8	IMP		Mouse	MGI:MGI:5644010|PMID:23812417
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Osbpl8	IMP		Mouse	PMID:21441927
Biological Process	GO:0090204	protein localization to nuclear pore	Osbpl8	IMP		Mouse	PMID:21441927

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern