Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ORC4
  • Mouse genes Orc4
  • Rat genes Orc4
  • Zfish genes orc4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Orc4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003688	DNA replication origin binding	ORC4	IMP		Human	PMID:9353276
Molecular Function	GO:0000166	nucleotide binding	ORC4	IDA		Human	PMID:9353276
Molecular Function	GO:0005515	protein binding	ORC4	IPI	UniProtKB:O43913	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	ORC4	IPI	UniProtKB:Q13416	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	ORC4	IPI	UniProtKB:Q9UBD5	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	ORC4	IPI	UniProtKB:Q9Y5N6	Human	PMID:15232106
Molecular Function	GO:0005515	protein binding	ORC4	IPI	UniProtKB:Q13416	Human	PMID:16549788
Molecular Function	GO:0005515	protein binding	ORC4	IPI	UniProtKB:O43913	Human	PMID:17716973
Molecular Function	GO:0005515	protein binding	ORC4	IPI	UniProtKB:Q13416	Human	PMID:17716973
Molecular Function	GO:0005515	protein binding	ORC4	IPI	UniProtKB:Q9UBD5	Human	PMID:17716973
Molecular Function	GO:0005515	protein binding	ORC4	IPI	UniProtKB:Q9Y5N6	Human	PMID:18234858
Molecular Function	GO:0005515	protein binding	ORC4	IPI	UniProtKB:P15884	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ORC4	IPI	UniProtKB:Q7LG56	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ORC4	IPI	UniProtKB:Q13416	Human	PMID:31467278
Cellular Component	GO:0000781	chromosome, telomeric region	ORC4	IDA		Human	PMID:24270157
Cellular Component	GO:0000781	chromosome, telomeric region	ORC4	HDA		Human	PMID:19135898
Cellular Component	GO:0005737	cytoplasm	Orc4	IDA		Mouse	PMID:28230328
Cellular Component	GO:0005829	cytosol	ORC4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005664	nuclear origin of replication recognition complex	ORC4	IDA		Human	PMID:20932478
Cellular Component	GO:0005730	nucleolus	ORC4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ORC4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ORC4	IDA		Human	PMID:21383955
Cellular Component	GO:0005634	nucleus	ORC4	IDA		Human	PMID:9353276
Cellular Component	GO:0000808	origin recognition complex	ORC4	IDA		Human	PMID:17716973
Biological Process	GO:0060271	cilium assembly	orc4	IMP	ZFIN:ZDB-MRPHLNO-190923-1	Zfish	PMID:30696958
Biological Process	GO:0006260	DNA replication	Orc4	IMP		Mouse	PMID:34977916
Biological Process	GO:0006270	DNA replication initiation	ORC4	IMP		Human	PMID:9353276
Biological Process	GO:0040038	polar body extrusion after meiotic divisions	Orc4	IMP		Mouse	PMID:34977916
Biological Process	GO:0040038	polar body extrusion after meiotic divisions	Orc4	IMP		Mouse	PMID:28230328
Biological Process	GO:0051258	protein polymerization	Orc4	IDA		Mouse	PMID:28230328

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern