Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes OPTC
  • Mouse genes Optc
  • Rat genes Optc
  • Zfish genes optc
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Optc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0031012	extracellular matrix	OPTC	IDA		Human	PMID:18164633
Cellular Component	GO:0031012	extracellular matrix	Optc	IDA		Mouse	PMID:22159013
Biological Process	GO:0001525	angiogenesis	Optc	IMP	MGI:MGI:5462239	Mouse	PMID:22159013
Biological Process	GO:0030199	collagen fibril organization	Optc	IMP		Mouse	MGI:MGI:6148629|PMID:29323130
Biological Process	GO:0016525	negative regulation of angiogenesis	Optc	IMP	MGI:MGI:5462239	Mouse	PMID:22159013

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern