Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NXN
  • Mouse genes Nxn
  • Rat genes Nxn
  • Zfish genes nxn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nxn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Nxn	IPI	UniProtKB:P30153|UniProtKB:P67775	Mouse	MGI:MGI:5508632|PMID:16764867
Molecular Function	GO:0005515	protein binding	Nxn	IPI	UniProtKB:Q9UGP8	Mouse	MGI:MGI:4939866|PMID:21251912
Molecular Function	GO:0005515	protein binding	Nxn	IPI	UniProtKB:O14640	Mouse	MGI:MGI:4943651|PMID:19643732
Molecular Function	GO:0005515	protein binding	Nxn	IPI	UniProtKB:Q61062	Mouse	MGI:MGI:5466648|PMID:23109420
Molecular Function	GO:0004791	thioredoxin-disulfide reductase activity	Nxn	IDA		Mouse	PMID:9119370
Cellular Component	GO:0005634	nucleus	Nxn	IDA		Mouse	PMID:9119370
Biological Process	GO:0098869	cellular oxidant detoxification	Nxn	IDA		Mouse	MGI:MGI:85780|PMID:9119370
Biological Process	GO:0072359	circulatory system development	Nxn	IMP		Mouse	MGI:MGI:4868553|PMID:20970343
Biological Process	GO:0001701	in utero embryonic development	Nxn	IMP	MGI:MGI:5548389	Mouse	PMID:27996060
Biological Process	GO:0031397	negative regulation of protein ubiquitination	Nxn	IMP		Mouse	MGI:MGI:4868553|PMID:20970343
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	Nxn	IMP		Mouse	MGI:MGI:4868553|PMID:20970343
Biological Process	GO:0016055	Wnt signaling pathway	NXN	IMP		Human	PMID:29276006

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern