| GO term: | thioredoxin-disulfide reductase activity |
| Synonym: | NADPH2:oxidized thioredoxin oxidoreductase activity |
| Synonym: | NADPH:oxidized thioredoxin oxidoreductase activity |
| Synonym: | NADPH--thioredoxin reductase activity |
| Synonym: | NADP--thioredoxin reductase activity |
| Synonym: | thioredoxin disulfide reductase activity |
| Synonym: | thioredoxin-disulphide reductase activity |
| Synonym: | thioredoxin:NADP+ oxidoreductase activity |
| Synonym: | thioredoxin reductase (NADPH) activity |
| GO id: | GO:0004791 |
| Definition: | Catalysis of the reaction: NADP(+) + thioredoxin = H(+) + NADPH + thioredoxin disulfide. |
| Number of paths to term: | 3 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functionantioxidant activityglutathione dehydrogenase (ascorbate) activityglutathione-disulfide reductase activityperoxidase activity +sulfiredoxin activitysuperoxide dismutase activitysuperoxide reductase activitythioredoxin-disulfide reductase activity [GO:0004791] (5 genes, 6 annotations)molecular_functioncatalytic activityoxidoreductase activityoxidoreductase activity, acting on a sulfur group of donorsoxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor2-oxopropyl-CoM reductase (carboxylating) activityalkyl hydroperoxide reductase activityasparagusate reductase activitybis-gamma-glutamylcystine reductase activityCoA-disulfide reductase activityCoA-glutathione reductase activitycystine reductase activitydihydrolipoyl dehydrogenase activityglutathione-disulfide reductase activityhypotaurine dehydrogenase activitymycothione reductase activityprotein-disulfide reductase activitysulfite reductase (NADPH) activitythioredoxin-disulfide reductase activity [GO:0004791] (5 genes, 6 annotations)trypanothione-disulfide reductase activitymolecular_functioncatalytic activityoxidoreductase activityoxidoreductase activity, acting on NAD(P)Hoxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor2-oxopropyl-CoM reductase (carboxylating) activityalkyl hydroperoxide reductase activityasparagusate reductase activitybis-gamma-glutamylcystine reductase activityCoA-disulfide reductase activityCoA-glutathione reductase activitycystine reductase activitydihydrolipoyl dehydrogenase activityglutathione-disulfide reductase activityhypotaurine dehydrogenase activitymycothione reductase activityprotein-disulfide reductase activitysulfite reductase (NADPH) activitythioredoxin-disulfide reductase activity [GO:0004791] (5 genes, 6 annotations)trypanothione-disulfide reductase activityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 05/08/2013 MGI 5.13 |
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