Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NUS1
  • Mouse genes Nus1
  • Rat genes Nus1
  • Zfish genes nus1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nus1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045547	dehydrodolichyl diphosphate synthase activity	NUS1	IDA		Human	PMID:28842490
Molecular Function	GO:0004659	prenyltransferase activity	NUS1	IDA		Human	PMID:25066056
Molecular Function	GO:0004659	prenyltransferase activity	Nus1	IMP		Mouse	PMID:25066056
Molecular Function	GO:0005515	protein binding	NUS1	IPI	UniProtKB:Q9H7T3	Human	PMID:21572394
Molecular Function	GO:0005515	protein binding	NUS1	IPI	UniProtKB:Q86SQ9	Human	PMID:32817466
Cellular Component	GO:1904423	dehydrodolichyl diphosphate synthase complex	NUS1	IPI		Human	PMID:32817466
Cellular Component	GO:1904423	dehydrodolichyl diphosphate synthase complex	NUS1	IDA		Human	PMID:28842490
Cellular Component	GO:0005789	endoplasmic reticulum membrane	NUS1	IDA		Human	PMID:19723497
Cellular Component	GO:0016020	membrane	Nus1	IMP		Mouse	PMID:25066056
Biological Process	GO:0042632	cholesterol homeostasis	Nus1	IMP		Mouse	PMID:25066056
Biological Process	GO:0019408	dolichol biosynthetic process	NUS1	IMP		Human	PMID:25066056
Biological Process	GO:0006489	dolichyl diphosphate biosynthetic process	NUS1	IDA		Human	PMID:28842490
Biological Process	GO:0006489	dolichyl diphosphate biosynthetic process	NUS1	IDA		Human	PMID:32817466
Biological Process	GO:0032367	intracellular cholesterol transport	nus1	IMP	ZFIN:ZDB-MRPHLNO-111209-1	Zfish	PMID:33731878
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	NUS1	IMP		Human	PMID:28602162
Biological Process	GO:0051000	positive regulation of nitric-oxide synthase activity	NUS1	IMP		Human	PMID:28602162
Biological Process	GO:0035268	protein mannosylation	Nus1	IMP		Mouse	PMID:25066056
Biological Process	GO:0032383	regulation of intracellular cholesterol transport	NUS1	IGI	UniProtKB:P61916	Human	PMID:19723497
Biological Process	GO:0032383	regulation of intracellular cholesterol transport	Nus1	IMP		Mouse	PMID:19723497
Biological Process	GO:0002040	sprouting angiogenesis	nus1	IMP	ZFIN:ZDB-MRPHLNO-111209-2	Zfish	PMID:20813898
Biological Process	GO:0002040	sprouting angiogenesis	nus1	IMP	ZFIN:ZDB-MRPHLNO-111209-1	Zfish	PMID:20813898
Biological Process	GO:0002040	sprouting angiogenesis	nus1	IMP	ZFIN:ZDB-MRPHLNO-111209-3	Zfish	PMID:20813898
Biological Process	GO:0055092	sterol homeostasis	Nus1	IMP		Mouse	PMID:19723497
Biological Process	GO:0036269	swimming behavior	nus1	IMP	ZFIN:ZDB-MRPHLNO-111209-1	Zfish	PMID:33731878
Biological Process	GO:0038084	vascular endothelial growth factor signaling pathway	NUS1	IMP		Human	PMID:28602162

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern