Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NTNG1
  • Mouse genes Ntng1
  • Rat genes Ntng1
  • Zfish genes ntng1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ntng1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	NTNG1	IPI	UniProtKB:Q9HCJ2	Human	PMID:23986473
Molecular Function	GO:0098632	cell-cell adhesion mediator activity	NTNG1	IGI	UniProtKB:Q9HCJ2	Human	PMID:23986473
Molecular Function	GO:0005515	protein binding	NTNG1	IPI	UniProtKB:Q9HCJ2	Human	PMID:14595443
Molecular Function	GO:0005515	protein binding	NTNG1	IPI	UniProtKB:Q9HBW1	Human	PMID:21946559
Molecular Function	GO:0005515	protein binding	NTNG1	IPI	UniProtKB:Q9HCJ2	Human	PMID:21946559
Molecular Function	GO:0005515	protein binding	Ntng1	IPI	PR:Q8C031	Mouse	PMID:16980967
Cellular Component	GO:0098978	glutamatergic synapse	Ntng1	IMP		Mouse	PMID:25411505
Cellular Component	GO:0098978	glutamatergic synapse	Ntng1	IDA		Mouse	PMID:25411505
Cellular Component	GO:0098978	glutamatergic synapse	Ntng1	IEP		Mouse	PMID:25411505
Cellular Component	GO:0005886	plasma membrane	NTNG1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Ntng1	IDA		Mouse	MGI:MGI:1888865|PMID:10964959
Cellular Component	GO:0005886	plasma membrane	Ntng1	IDA		Mouse	PMID:11804778
Cellular Component	GO:0048787	presynaptic active zone membrane	Ntng1	IDA		Mouse	PMID:25411505
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Ntng1	IDA		Mouse	PMID:25411505
Biological Process	GO:0007409	axonogenesis	Ntng1	IDA		Mouse	PMID:11804778
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Ntng1	IDA		Mouse	PMID:25411505
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Ntng1	IMP		Mouse	PMID:25411505
Biological Process	GO:2001222	regulation of neuron migration	Ntng1	IMP		Mouse	MGI:MGI:6415477|PMID:31692205
Biological Process	GO:0150011	regulation of neuron projection arborization	Ntng1	IMP		Mouse	MGI:MGI:6415477|PMID:31692205
Biological Process	GO:0010975	regulation of neuron projection development	Ntng1	IMP		Mouse	MGI:MGI:6415477|PMID:31692205
Biological Process	GO:0099560	synaptic membrane adhesion	NTNG1	IGI	UniProtKB:Q9HCJ2	Human	PMID:23986473
Biological Process	GO:0099560	synaptic membrane adhesion	Ntng1	IDA		Mouse	PMID:25411505
Biological Process	GO:0099560	synaptic membrane adhesion	Ntng1	IEP		Mouse	PMID:25411505
Biological Process	GO:0099560	synaptic membrane adhesion	Ntng1	IMP		Mouse	PMID:25411505

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern