Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NPTX2
  • Mouse genes Nptx2
  • Rat genes Nptx2
  • Zfish genes nptx2a,nptx2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nptx2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NPTX2	IPI	UniProtKB:O60353	Human	PMID:30833544
Cellular Component	GO:0098892	extrinsic component of postsynaptic specialization membrane	Nptx2	IDA		Rat	PMID:10399937|RGD:13702159
Cellular Component	GO:0098892	extrinsic component of postsynaptic specialization membrane	Nptx2	IMP		Rat	PMID:10399937|RGD:13702159
Cellular Component	GO:0098978	glutamatergic synapse	NPTX2	IDA		Human	PMID:27986928
Cellular Component	GO:0098978	glutamatergic synapse	NPTX2	IMP		Human	PMID:27986928
Cellular Component	GO:0098978	glutamatergic synapse	Nptx2	IDA		Rat	PMID:10399937|RGD:13702159
Cellular Component	GO:0098978	glutamatergic synapse	Nptx2	IMP		Rat	PMID:10399937|RGD:13702159
Cellular Component	GO:0043083	synaptic cleft	Nptx2	IDA		Rat	PMID:10399937|RGD:13702159
Cellular Component	GO:0043083	synaptic cleft	Nptx2	IMP		Rat	PMID:10399937|RGD:13702159
Biological Process	GO:0008306	associative learning	Nptx2	IMP	MGI:MGI:3765981	Mouse	PMID:18057201
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Nptx2	IDA		Rat	PMID:10399937|RGD:13702159
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Nptx2	IMP		Rat	PMID:10399937|RGD:13702159
Biological Process	GO:0042752	regulation of circadian rhythm	nptx2b	IMP	ZFIN:ZDB-GENO-110328-4	Zfish	PMID:20920793
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	nptx2b	IMP	ZFIN:ZDB-GENO-110328-4	Zfish	PMID:20920793
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	NPTX2	IDA		Human	PMID:27986928
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	NPTX2	IMP		Human	PMID:27986928
Biological Process	GO:0051966	regulation of synaptic transmission, glutamatergic	nptx2a	IMP	ZFIN:ZDB-GENO-150610-6	Zfish	PMID:25466900

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern