Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NPNT
  • Mouse genes Npnt
  • Rat genes Npnt
  • Zfish genes npnta
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Npnt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005178	integrin binding	Npnt	IDA		Mouse	MGI:MGI:5306572|PMID:19342381
Molecular Function	GO:0005178	integrin binding	Npnt	IPI	PR:Q3V3R4	Mouse	PMID:11546798
Cellular Component	GO:0005604	basement membrane	Npnt	IDA		Mouse	MGI:MGI:4947862|PMID:21335239
Cellular Component	GO:0005604	basement membrane	Npnt	IDA		Mouse	PMID:18757743
Cellular Component	GO:0062023	collagen-containing extracellular matrix	NPNT	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	NPNT	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Npnt	IDA		Mouse	MGI:MGI:4947862|PMID:21335239
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Npnt	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0070062	extracellular exosome	NPNT	HDA		Human	PMID:19199708
Cellular Component	GO:0031012	extracellular matrix	Npnt	IDA		Mouse	PMID:11546798
Cellular Component	GO:0031012	extracellular matrix	Npnt	IDA		Mouse	PMID:11470831
Cellular Component	GO:0031012	extracellular matrix	Npnt	IPI	UniProtKB:Q8BPT3	Mouse	PMID:11470831
Cellular Component	GO:0005576	extracellular region	Npnt	IDA		Mouse	MGI:MGI:4414689|PMID:19944102
Cellular Component	GO:0030485	smooth muscle contractile fiber	Npnt	IDA		Mouse	MGI:MGI:4947862|PMID:21335239
Biological Process	GO:0003171	atrioventricular valve development	npnta	IGI	ZFIN:ZDB-MRPHLNO-060930-5,ZFIN:ZDB-MRPHLNO-111018-2	Zfish	PMID:21937601
Biological Process	GO:0003171	atrioventricular valve development	npnta	IMP	ZFIN:ZDB-MRPHLNO-111018-2	Zfish	PMID:21937601
Biological Process	GO:0003171	atrioventricular valve development	npnta	IMP	ZFIN:ZDB-MRPHLNO-111018-1	Zfish	PMID:21937601
Biological Process	GO:0003171	atrioventricular valve development	npnta	IMP	ZFIN:ZDB-MRPHLNO-111018-3	Zfish	PMID:21937601
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	Npnt	IMP	MGI:MGI:3715213	Mouse	PMID:17537792
Biological Process	GO:0033631	cell-cell adhesion mediated by integrin	Npnt	IDA		Mouse	MGI:MGI:5306572|PMID:19342381
Biological Process	GO:0007160	cell-matrix adhesion	Npnt	IPI	UniProtKB:Q8BPT3	Mouse	PMID:11470831
Biological Process	GO:0007160	cell-matrix adhesion	Npnt	IDA		Mouse	PMID:11546798
Biological Process	GO:0007160	cell-matrix adhesion	Npnt	IDA		Mouse	PMID:11470831
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Npnt	IDA		Mouse	MGI:MGI:5285024|PMID:21689636
Biological Process	GO:0045184	establishment of protein localization	Npnt	IMP		Mouse	MGI:MGI:4947862|PMID:21335239
Biological Process	GO:0030198	extracellular matrix organization	Npnt	IDA		Mouse	PMID:18757743
Biological Process	GO:0060347	heart trabecula formation	npnta	IMP	ZFIN:ZDB-MRPHLNO-111018-2	Zfish	PMID:21937601
Biological Process	GO:0097195	pilomotor reflex	Npnt	IMP		Mouse	MGI:MGI:4947862|PMID:21335239
Biological Process	GO:0010694	positive regulation of alkaline phosphatase activity	Npnt	IDA		Mouse	MGI:MGI:4414689|PMID:19944102
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	Npnt	IDA		Mouse	PMID:18757743
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Npnt	IDA		Mouse	MGI:MGI:4414689|PMID:19944102
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Npnt	IMP		Mouse	MGI:MGI:5285024|PMID:21689636
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	Npnt	IMP		Mouse	MGI:MGI:4414689|PMID:19944102
Biological Process	GO:0045987	positive regulation of smooth muscle contraction	Npnt	IMP		Mouse	MGI:MGI:4947862|PMID:21335239
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Npnt	IDA		Mouse	MGI:MGI:4947862|PMID:21335239
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	Npnt	IMP	MGI:MGI:3715213	Mouse	PMID:17537792
Biological Process	GO:0051145	smooth muscle cell differentiation	Npnt	IDA		Mouse	MGI:MGI:4947862|PMID:21335239
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Npnt	IMP	MGI:MGI:3715213	Mouse	PMID:17537792
Biological Process	GO:0001657	ureteric bud development	Npnt	IMP	MGI:MGI:3715213	Mouse	PMID:17537792

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern