Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NOVA2
  • Mouse genes Nova2
  • Rat genes Nova2
  • Zfish genes nova2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nova2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003729	mRNA binding	Nova2	IDA		Mouse	MGI:MGI:6718240|PMID:14615540
Molecular Function	GO:0005515	protein binding	Nova2	IPI	UniProtKB:Q9QYC2	Mouse	PMID:10829067
Molecular Function	GO:0003723	RNA binding	NOVA2	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	NOVA2	IDA		Human	PMID:32197073
Molecular Function	GO:0003723	RNA binding	Nova2	IDA		Mouse	PMID:9789075
Molecular Function	GO:1990825	sequence-specific mRNA binding	NOVA2	IDA		Human	PMID:10811881
Biological Process	GO:0021954	central nervous system neuron development	Nova2	IMP		Mouse	MGI:MGI:5789071|PMID:27223325
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	Nova2	IGI	UniProtKB:A0A1W2P872,UniProtKB:Q9JKN6	Mouse	MGI:MGI:5810478|PMID:27635635
Biological Process	GO:0030182	neuron differentiation	NOVA2	IMP		Human	PMID:32197073
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	NOVA2	IMP		Human	PMID:32197073
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Nova2	IMP		Mouse	MGI:MGI:6716952|PMID:17065982
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Nova2	IMP		Mouse	MGI:MGI:6718240|PMID:14615540
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Nova2	IMP		Mouse	MGI:MGI:3587155|PMID:16041372
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Nova2	IMP		Mouse	MGI:MGI:5789071|PMID:27223325
Biological Process	GO:1902667	regulation of axon guidance	Nova2	IMP		Mouse	MGI:MGI:5789071|PMID:27223325
Biological Process	GO:0051252	regulation of RNA metabolic process	NOVA2	IMP		Human	PMID:32197073
Biological Process	GO:0051252	regulation of RNA metabolic process	Nova2	IGI	MGI:MGI:104297	Mouse	PMID:23359859

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern