Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NLRP10
  • Mouse genes Nlrp10
  • Rat genes Nlrp10
  • Zfish genes nlrb5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nlrp10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016887	ATP hydrolysis activity	NLRP10	IDA		Human	PMID:23861819
Molecular Function	GO:0003924	GTPase activity	NLRP10	IDA		Human	PMID:23861819
Cellular Component	GO:0005737	cytoplasm	NLRP10	IDA		Human	PMID:22672233
Cellular Component	GO:0005737	cytoplasm	nlrb5	IDA		Zfish	PMID:24858030
Cellular Component	GO:0005829	cytosol	NLRP10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0019897	extrinsic component of plasma membrane	NLRP10	IDA		Human	PMID:22672233
Cellular Component	GO:0031965	nuclear membrane	NLRP10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NLRP10	IDA		Human	GO_REF:0000052
Biological Process	GO:0050832	defense response to fungus	Nlrp10	IMP		Mouse	MGI:MGI:5449483|PMID:23071280
Biological Process	GO:0050829	defense response to Gram-negative bacterium	NLRP10	IMP		Human	PMID:22672233
Biological Process	GO:1900426	positive regulation of defense response to bacterium	NLRP10	IMP		Human	PMID:28766990
Biological Process	GO:0050729	positive regulation of inflammatory response	Nlrp10	IMP		Mouse	MGI:MGI:5914718|PMID:27221772
Biological Process	GO:0032730	positive regulation of interleukin-1 alpha production	NLRP10	IMP		Human	PMID:28766990
Biological Process	GO:0032755	positive regulation of interleukin-6 production	NLRP10	IMP		Human	PMID:22672233
Biological Process	GO:0032757	positive regulation of interleukin-8 production	NLRP10	IMP		Human	PMID:22672233
Biological Process	GO:0002827	positive regulation of T-helper 1 type immune response	Nlrp10	IMP		Mouse	MGI:MGI:5449483|PMID:23071280
Biological Process	GO:2000318	positive regulation of T-helper 17 type immune response	Nlrp10	IMP		Mouse	MGI:MGI:5449483|PMID:23071280

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern