Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NHP2
  • Mouse genes Nhp2
  • Rat genes Nhp2
  • Zfish genes nhp2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nhp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034513	box H/ACA snoRNA binding	NHP2	IPI	RNAcentral:URS0000210FD6_9606	Human	PMID:18082603
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Nhp2	IDA		Rat	PMID:15044956|RGD:10766448
Molecular Function	GO:0005515	protein binding	NHP2	IPI	UniProtKB:Q6NT76	Human	PMID:23685356
Molecular Function	GO:0005515	protein binding	NHP2	IPI	UniProtKB:Q9NPE3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NHP2	IPI	UniProtKB:Q9NPE3	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	NHP2	IPI	UniProtKB:Q9NPE3	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	NHP2	IPI	UniProtKB:Q9NPE3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NHP2	IPI	UniProtKB:Q9NPE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NHP2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Nhp2	IPI	UniProtKB:Q8BJA3	Mouse	MGI:MGI:5500098|PMID:23685356
Molecular Function	GO:0003723	RNA binding	NHP2	IPI	RNAcentral:URS00004416C5_9606	Human	PMID:18082603
Molecular Function	GO:0003723	RNA binding	NHP2	IPI	RNAcentral:URS00004416C5_9606	Human	PMID:20351177
Molecular Function	GO:0003723	RNA binding	NHP2	IPI	RNAcentral:URS00004416C5_9606	Human	PMID:22527283
Molecular Function	GO:0003723	RNA binding	NHP2	HDA		Human	PMID:22658674
Molecular Function	GO:0070034	telomerase RNA binding	NHP2	IPI	RNAcentral:URS00004A7003_9606	Human	PMID:18082603
Molecular Function	GO:0070034	telomerase RNA binding	NHP2	IPI	RNAcentral:URS00004A7003_9606	Human	PMID:20351177
Molecular Function	GO:0070034	telomerase RNA binding	NHP2	IPI	RNAcentral:URS00004A7003_9606	Human	PMID:22527283
Molecular Function	GO:0034511	U3 snoRNA binding	Nhp2	IDA		Rat	PMID:15044956|RGD:10766448
Cellular Component	GO:0031429	box H/ACA snoRNP complex	NHP2	IDA		Human	PMID:18082603
Cellular Component	GO:0031429	box H/ACA snoRNP complex	Nhp2	IDA		Rat	PMID:12446766|RGD:633420
Cellular Component	GO:0090661	box H/ACA telomerase RNP complex	NHP2	IDA		Human	PMID:18082603
Cellular Component	GO:0000781	chromosome, telomeric region	NHP2	HDA		Human	PMID:19135898
Cellular Component	GO:0005697	telomerase holoenzyme complex	NHP2	IDA		Human	PMID:18082603
Cellular Component	GO:0005697	telomerase holoenzyme complex	NHP2	IDA		Human	PMID:29695869
Biological Process	GO:1904874	positive regulation of telomerase RNA localization to Cajal body	NHP2	HMP		Human	PMID:25467444
Biological Process	GO:0000454	snoRNA guided rRNA pseudouridine synthesis	Nhp2	IDA		Rat	PMID:12446766|RGD:633420
Biological Process	GO:0007004	telomere maintenance via telomerase	NHP2	IDA		Human	PMID:29695869

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern