Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NFRKB
  • Mouse genes Nfrkb
  • Rat genes Nfrkb
  • Zfish genes nfrkb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfrkb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002020	protease binding	NFRKB	IPI	UniProtKB:Q9Y5K5	Human	PMID:18922472
Molecular Function	GO:0005515	protein binding	NFRKB	IPI	UniProtKB:Q9Y5K5	Human	PMID:18922472
Molecular Function	GO:0005515	protein binding	NFRKB	IPI	UniProtKB:Q9Y5K5	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	NFRKB	IPI	UniProtKB:Q9Y5K5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NFRKB	IPI	UniProtKB:Q9Y5K5-3	Human	PMID:32296183
Cellular Component	GO:0031011	Ino80 complex	NFRKB	IDA		Human	PMID:21303910
Cellular Component	GO:0005654	nucleoplasm	NFRKB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NFRKB	IDA		Human	PMID:18922472
Biological Process	GO:0006338	chromatin remodeling	NFRKB	IDA		Human	PMID:21303910
Biological Process	GO:0045739	positive regulation of DNA repair	Nfrkb	IDA		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NFRKB	IMP		Human	PMID:27641337
Biological Process	GO:1904507	positive regulation of telomere maintenance in response to DNA damage	Nfrkb	IMP		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0051726	regulation of cell cycle	NFRKB	IMP		Human	PMID:26340092
Biological Process	GO:0033044	regulation of chromosome organization	NFRKB	IMP		Human	PMID:26340092
Biological Process	GO:0006282	regulation of DNA repair	Nfrkb	IDA		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0006275	regulation of DNA replication	NFRKB	IMP		Human	PMID:25016522
Biological Process	GO:0060382	regulation of DNA strand elongation	NFRKB	IMP		Human	PMID:25016522
Biological Process	GO:0045995	regulation of embryonic development	Nfrkb	IMP		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0000723	telomere maintenance	Nfrkb	IMP		Mouse	MGI:MGI:5638510|PMID:23979016

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern