Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NEXN
  • Mouse genes Nexn
  • Rat genes Nexn
  • Zfish genes nexn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nexn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	NEXN	IDA		Human	PMID:15823560
Molecular Function	GO:0051015	actin filament binding	Nexn	IDA		Rat	PMID:9832551|RGD:1299387
Molecular Function	GO:0008307	structural constituent of muscle	NEXN	IMP		Human	PMID:19881492
Cellular Component	GO:0015629	actin cytoskeleton	NEXN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030055	cell-substrate junction	Nexn	IDA		Rat	PMID:9832551|RGD:1299387
Cellular Component	GO:0005925	focal adhesion	NEXN	HDA		Human	PMID:21423176
Cellular Component	GO:0005925	focal adhesion	Nexn	IDA		Rat	PMID:9832551|RGD:1299387
Cellular Component	GO:0005886	plasma membrane	NEXN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030018	Z disc	Nexn	IDA		Rat	PMID:19881492|RGD:8553584
Cellular Component	GO:0030018	Z disc	nexn	IDA		Zfish	PMID:19881492
Biological Process	GO:0055013	cardiac muscle cell development	nexn	IMP	ZFIN:ZDB-MRPHLNO-091216-13	Zfish	PMID:19881492
Biological Process	GO:0030334	regulation of cell migration	NEXN	IDA		Human	PMID:15823560
Biological Process	GO:0051493	regulation of cytoskeleton organization	NEXN	IEP		Human	PMID:15823560
Biological Process	GO:0009617	response to bacterium	Nexn	IEP		Mouse	PMID:23012479

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern