Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NEU3
  • Mouse genes Neu3
  • Rat genes Neu3
  • Zfish genes neu3.1,neu3.2,neu3.3,neu3.4,neu3.5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Neu3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016997	alpha-sialidase activity	NEU3	IDA		Human	PMID:12730204
Molecular Function	GO:0016997	alpha-sialidase activity	neu3.1	IDA		Zfish	PMID:32980954
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	NEU3	IDA		Human	PMID:11298736
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	NEU3	IDA		Human	PMID:15847605
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	NEU3	IDA		Human	PMID:17334392
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	Neu3	IDA		Mouse	MGI:MGI:6478528|PMID:11696012
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	Neu3	IDA		Mouse	MGI:MGI:3040535|PMID:14970224
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	Neu3	IDA		Mouse	MGI:MGI:3765376|PMID:17708748
Molecular Function	GO:0052796	exo-alpha-(2->8)-sialidase activity	NEU3	IDA		Human	PMID:15847605
Molecular Function	GO:0004308	exo-alpha-sialidase activity	NEU3	IDA		Human	PMID:10861246
Molecular Function	GO:0004308	exo-alpha-sialidase activity	neu3.2	IDA		Zfish	PMID:17708749
Molecular Function	GO:0004308	exo-alpha-sialidase activity	neu3.3	IDA		Zfish	PMID:17708749
Molecular Function	GO:0004308	exo-alpha-sialidase activity	neu3.1	IDA		Zfish	PMID:17708749
Molecular Function	GO:0005515	protein binding	NEU3	IPI	UniProtKB:P00533	Human	PMID:17334392
Cellular Component	GO:0005829	cytosol	neu3.2	IDA		Zfish	PMID:17708749
Cellular Component	GO:0031901	early endosome membrane	NEU3	IDA		Human	PMID:26251452
Cellular Component	GO:0031901	early endosome membrane	Neu3	IDA		Mouse	MGI:MGI:3765376|PMID:17708748
Cellular Component	GO:0005783	endoplasmic reticulum	neu3.1	IDA		Zfish	PMID:17708749
Cellular Component	GO:0009897	external side of plasma membrane	Neu3	IDA		Mouse	MGI:MGI:3765376|PMID:17708748
Cellular Component	GO:0005765	lysosomal membrane	NEU3	IDA		Human	PMID:26251452
Cellular Component	GO:0016020	membrane	neu3.3	IDA		Zfish	PMID:17708749
Cellular Component	GO:0005886	plasma membrane	NEU3	IDA		Human	PMID:12730204
Cellular Component	GO:0005886	plasma membrane	NEU3	IDA		Human	PMID:26251452
Cellular Component	GO:0005886	plasma membrane	Neu3	IDA		Mouse	MGI:MGI:3040535|PMID:14970224
Cellular Component	GO:0055038	recycling endosome membrane	NEU3	IDA		Human	PMID:26251452
Cellular Component	GO:0055038	recycling endosome membrane	Neu3	IDA		Mouse	MGI:MGI:3765376|PMID:17708748
Biological Process	GO:0005975	carbohydrate metabolic process	NEU3	IDA		Human	PMID:12730204
Biological Process	GO:0006689	ganglioside catabolic process	NEU3	IDA		Human	PMID:10861246
Biological Process	GO:0006689	ganglioside catabolic process	NEU3	IDA		Human	PMID:11298736
Biological Process	GO:0006689	ganglioside catabolic process	NEU3	IDA		Human	PMID:15847605
Biological Process	GO:0006689	ganglioside catabolic process	NEU3	IDA		Human	PMID:17334392
Biological Process	GO:0006689	ganglioside catabolic process	Neu3	IDA		Mouse	MGI:MGI:6478528|PMID:11696012
Biological Process	GO:0006689	ganglioside catabolic process	Neu3	IDA		Mouse	MGI:MGI:3040535|PMID:14970224
Biological Process	GO:0006689	ganglioside catabolic process	Neu3	IDA		Mouse	MGI:MGI:3765376|PMID:17708748
Biological Process	GO:0001573	ganglioside metabolic process	neu3.3	IDA		Zfish	PMID:17708749
Biological Process	GO:0001573	ganglioside metabolic process	neu3.1	IDA		Zfish	PMID:17708749
Biological Process	GO:1900186	negative regulation of clathrin-dependent endocytosis	NEU3	IDA		Human	PMID:26251452
Biological Process	GO:0009313	oligosaccharide catabolic process	NEU3	IDA		Human	PMID:10861246
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	NEU3	IMP		Human	PMID:17334392

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern