Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NEU2
  • Mouse genes Neu2
  • Rat genes Neu2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Neu2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	NEU2	IDA		Human	PMID:14613940
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	NEU2	IDA		Human	PMID:22228546
Molecular Function	GO:0052794	exo-alpha-(2->3)-sialidase activity	Neu2	IDA		Mouse	MGI:MGI:1354405|PMID:10713120
Molecular Function	GO:0052796	exo-alpha-(2->8)-sialidase activity	NEU2	IDA		Human	PMID:14613940
Molecular Function	GO:0052796	exo-alpha-(2->8)-sialidase activity	Neu2	IDA		Mouse	MGI:MGI:1354405|PMID:10713120
Molecular Function	GO:0004308	exo-alpha-sialidase activity	NEU2	IDA		Human	PMID:26193330
Molecular Function	GO:0004308	exo-alpha-sialidase activity	Neu2	IDA		Rat	PMID:15710387|RGD:2316559
Molecular Function	GO:0005515	protein binding	NEU2	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NEU2	IPI	UniProtKB:Q7Z3S9	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	NEU2	IPI	UniProtKB:Q9H227	Human	PMID:26193330
Molecular Function	GO:0005515	protein binding	NEU2	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Cellular Component	GO:1902494	catalytic complex	NEU2	IDA		Human	PMID:26193330
Cellular Component	GO:0005737	cytoplasm	Neu2	IDA		Rat	PMID:9311229|RGD:2316561
Cellular Component	GO:0005829	cytosol	NEU2	IDA		Human	PMID:10561456
Cellular Component	GO:0005829	cytosol	NEU2	IDA		Human	PMID:26193330
Cellular Component	GO:0005829	cytosol	Neu2	IDA		Rat	PMID:12860410|RGD:2316560
Biological Process	GO:0006689	ganglioside catabolic process	NEU2	IDA		Human	PMID:14613940
Biological Process	GO:0006689	ganglioside catabolic process	NEU2	IDA		Human	PMID:22228546
Biological Process	GO:0006689	ganglioside catabolic process	Neu2	IDA		Mouse	MGI:MGI:1354405|PMID:10713120
Biological Process	GO:0006516	glycoprotein catabolic process	NEU2	IDA		Human	PMID:14613940
Biological Process	GO:0009313	oligosaccharide catabolic process	NEU2	IDA		Human	PMID:14613940
Biological Process	GO:0009313	oligosaccharide catabolic process	NEU2	IDA		Human	PMID:22228546
Biological Process	GO:0009313	oligosaccharide catabolic process	NEU2	IDA		Human	PMID:26193330
Biological Process	GO:0009313	oligosaccharide catabolic process	Neu2	IDA		Mouse	MGI:MGI:1354405|PMID:10713120
Biological Process	GO:0045663	positive regulation of myoblast differentiation	Neu2	IDA		Rat	PMID:12860410|RGD:2316560
Biological Process	GO:0010831	positive regulation of myotube differentiation	Neu2	IMP		Rat	PMID:8630046|RGD:2316563
Biological Process	GO:0045471	response to ethanol	Neu2	IEP		Rat	PMID:16713441|RGD:2316558

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern