Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NELFA
  • Mouse genes Nelfa
  • Rat genes Nelfa
  • Zfish genes nelfa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nelfa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Nelfa	IDA		Mouse	PMID:21670248
Molecular Function	GO:0003682	chromatin binding	Nelfa	IMP		Rat	PMID:21623364|RGD:9693718
Molecular Function	GO:0060090	molecular adaptor activity	NELFA	IDA		Human	PMID:30135580
Molecular Function	GO:0060090	molecular adaptor activity	NELFA	IPI	UniProtKB:I3LGP4,UniProtKB:I3LJR4,UniProtKB:O00267,UniProtKB:P60899,UniProtKB:P63272	Human	PMID:30135580
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:Q8IXH7-4	Human	PMID:12612062
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:Q8IXH7	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:Q8IXH7	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:Q8IUQ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:Q8IXH7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:Q8IXH7-4	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:P35372	Human	PMID:28298427
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:Q8IXH7-4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:O43639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:P40692	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:Q00526	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:Q13526	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:Q8IXH7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:Q96B97	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NELFA	IPI	UniProtKB:Q96GM5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Nelfa	IPI	UniProtKB:Q8C4Y3	Mouse	MGI:MGI:6250769|PMID:26010750
Cellular Component	GO:0005829	cytosol	NELFA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032021	NELF complex	NELFA	IPI		Human	PMID:12612062
Cellular Component	GO:0032021	NELF complex	NELFA	IDA		Human	PMID:12612062
Cellular Component	GO:0016604	nuclear body	NELFA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NELFA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NELFA	IDA		Human	PMID:12612062
Cellular Component	GO:0005634	nucleus	Nelfa	IDA		Mouse	PMID:19796622
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	NELFA	IDA		Human	PMID:12612062
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	Nelfa	IMP		Mouse	PMID:21670248
Biological Process	GO:0051571	positive regulation of histone H3-K4 methylation	Nelfa	IMP		Rat	PMID:21623364|RGD:9693718
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nelfa	IMP		Rat	PMID:21623364|RGD:9693718

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern