Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NEK11
  • Mouse genes Nek11
  • Rat genes Nek11
  • Zfish genes nek11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nek11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	NEK11	IDA		Human	PMID:15161910
Molecular Function	GO:0005515	protein binding	NEK11	IPI	UniProtKB:P51955	Human	PMID:15161910
Molecular Function	GO:0005515	protein binding	NEK11	IPI	UniProtKB:P51955-1	Human	PMID:15161910
Molecular Function	GO:0005515	protein binding	NEK11	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	NEK11	IPI	UniProtKB:P08238	Human	PMID:32707033
Molecular Function	GO:0004674	protein serine/threonine kinase activity	NEK11	IDA		Human	PMID:15161910
Molecular Function	GO:0004674	protein serine/threonine kinase activity	NEK11	IDA		Human	PMID:19734889
Cellular Component	GO:0005730	nucleolus	NEK11	IDA		Human	PMID:15161910
Cellular Component	GO:0005654	nucleoplasm	NEK11	IDA		Human	GO_REF:0000052
Biological Process	GO:0035556	intracellular signal transduction	NEK11	IDA		Human	PMID:15161910
Biological Process	GO:0031573	mitotic intra-S DNA damage checkpoint signaling	NEK11	IDA		Human	PMID:15161910
Biological Process	GO:0006468	protein phosphorylation	NEK11	IDA		Human	PMID:15161910
Biological Process	GO:0006468	protein phosphorylation	NEK11	IDA		Human	PMID:19734889
Biological Process	GO:1901990	regulation of mitotic cell cycle phase transition	NEK11	IMP		Human	PMID:12154088

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern