Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NCS1
  • Mouse genes Ncs1
  • Rat genes Ncs1
  • Zfish genes ncs1a,ncs1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ncs1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	Ncs1	IDA		Rat	PMID:18199453|RGD:7241275
Molecular Function	GO:0000287	magnesium ion binding	Ncs1	IDA		Rat	PMID:18199453|RGD:7241275
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q9NZN1	Human	PMID:12783849
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q86UW9	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q86UW9	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:P41271	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q86UW9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:A0A1U9X8X8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:O60930	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:O75084	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:O95868	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:P10451	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:P78358	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q03060-25	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q7Z698	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q86UW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q8IWL1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q8TDS5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q96C03-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q96K80	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q96ST8-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q9BXJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q9UKN5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NCS1	IPI	UniProtKB:Q9Y336	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ncs1	IPI	UniProtKB:P14100	Rat	PMID:16470652|RGD:8554798
Molecular Function	GO:0005515	protein binding	Ncs1	IPI	UniProtKB:P84080	Rat	PMID:16470652|RGD:8554798
Molecular Function	GO:0019901	protein kinase binding	Ncs1	IPI	RGD:621214	Rat	PMID:12244129|RGD:7241276
Molecular Function	GO:0005245	voltage-gated calcium channel activity	Ncs1	IMP		Rat	PMID:17502602|RGD:8553610
Cellular Component	GO:0030424	axon	Ncs1	IDA		Mouse	PMID:9030700
Cellular Component	GO:0044305	calyx of Held	Ncs1	IDA		Rat	PMID:11910115|RGD:13702284
Cellular Component	GO:0044305	calyx of Held	Ncs1	IMP		Rat	PMID:11910115|RGD:13702284
Cellular Component	GO:0005737	cytoplasm	NCS1	IDA		Human	PMID:12783849
Cellular Component	GO:0031410	cytoplasmic vesicle	Ncs1	IDA		Rat	PMID:12034721|RGD:728470
Cellular Component	GO:0005829	cytosol	Ncs1	IDA		Rat	PMID:12034721|RGD:728470
Cellular Component	GO:0005829	cytosol	Ncs1	IDA		Rat	PMID:12244129|RGD:7241276
Cellular Component	GO:0030425	dendrite	Ncs1	IDA		Mouse	PMID:9030700
Cellular Component	GO:0031045	dense core granule	Ncs1	IDA		Rat	PMID:9712909|RGD:2316314
Cellular Component	GO:0098978	glutamatergic synapse	Ncs1	IDA		Rat	PMID:12947410|RGD:13702435
Cellular Component	GO:0098978	glutamatergic synapse	Ncs1	IMP		Rat	PMID:12947410|RGD:13702435
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	NCS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	NCS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	NCS1	IDA		Human	PMID:12783849
Cellular Component	GO:0005886	plasma membrane	Ncs1	IDA		Rat	PMID:12034721|RGD:728470
Cellular Component	GO:0005886	plasma membrane	Ncs1	IDA		Rat	PMID:12244129|RGD:7241276
Cellular Component	GO:0098794	postsynapse	Ncs1	IDA		Rat	PMID:12351722|RGD:13702158
Cellular Component	GO:0099524	postsynaptic cytosol	Ncs1	IDA		Rat	PMID:11910115|RGD:13702284
Cellular Component	GO:0099523	presynaptic cytosol	Ncs1	IDA		Rat	PMID:11910115|RGD:13702284
Biological Process	GO:0048015	phosphatidylinositol-mediated signaling	Ncs1	IDA		Rat	PMID:12034721|RGD:728470
Biological Process	GO:0045921	positive regulation of exocytosis	Ncs1	IDA		Rat	PMID:12034721|RGD:728470
Biological Process	GO:0045921	positive regulation of exocytosis	Ncs1	IDA		Rat	PMID:9712909|RGD:2316314
Biological Process	GO:0010975	regulation of neuron projection development	Ncs1	IMP		Rat	PMID:17502602|RGD:8553610
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Ncs1	IDA		Rat	PMID:11910115|RGD:13702284
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Ncs1	IMP		Rat	PMID:11910115|RGD:13702284
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Ncs1	IDA		Rat	PMID:12947410|RGD:13702435
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Ncs1	IMP		Rat	PMID:12947410|RGD:13702435
Biological Process	GO:0060872	semicircular canal development	ncs1a	IGI	ZFIN:ZDB-MRPHLNO-050930-1,ZFIN:ZDB-MRPHLNO-090818-6	Zfish	PMID:19320994
Biological Process	GO:0060872	semicircular canal development	ncs1a	IGI	ZFIN:ZDB-MRPHLNO-050930-1,ZFIN:ZDB-MRPHLNO-090818-5	Zfish	PMID:19320994
Biological Process	GO:0048752	semicircular canal morphogenesis	ncs1a	IMP	ZFIN:ZDB-MRPHLNO-050930-1	Zfish	PMID:15898063
Biological Process	GO:0048752	semicircular canal morphogenesis	ncs1a	IMP	ZFIN:ZDB-MRPHLNO-050930-4	Zfish	PMID:15898063

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern