Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MZB1
  • Mouse genes Mzb1
  • Rat genes Mzb1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mzb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MZB1	IPI	UniProtKB:Q99816	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Mzb1	IPI	UniProtKB:P08113|UniProtKB:P27773	Mouse	MGI:MGI:4866969|PMID:21093319
Cellular Component	GO:0034663	endoplasmic reticulum chaperone complex	Mzb1	IDA		Mouse	MGI:MGI:4421284|PMID:19805157
Cellular Component	GO:0005788	endoplasmic reticulum lumen	Mzb1	IDA		Mouse	MGI:MGI:4866969|PMID:21093319
Cellular Component	GO:0005576	extracellular region	Mzb1	IDA		Mouse	MGI:MGI:5141331|PMID:21688198
Biological Process	GO:0033622	integrin activation	Mzb1	IMP		Mouse	MGI:MGI:4866969|PMID:21093319
Biological Process	GO:0008284	positive regulation of cell population proliferation	Mzb1	IDA		Mouse	MGI:MGI:5141331|PMID:21688198
Biological Process	GO:0002639	positive regulation of immunoglobulin production	Mzb1	IMP		Mouse	MGI:MGI:4366098|PMID:19805154
Biological Process	GO:0002639	positive regulation of immunoglobulin production	Mzb1	IMP		Mouse	MGI:MGI:4421284|PMID:19805157
Biological Process	GO:0030888	regulation of B cell proliferation	Mzb1	IMP		Mouse	MGI:MGI:4866969|PMID:21093319
Biological Process	GO:0042127	regulation of cell population proliferation	Mzb1	IMP		Mouse	MGI:MGI:4866969|PMID:21093319
Biological Process	GO:0046626	regulation of insulin receptor signaling pathway	Mzb1	IDA		Mouse	MGI:MGI:5141331|PMID:21688198

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern